سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

ساعی قره‌ناز, دکتر مرضیه, رستمی دوم, مرضیه, رمضانی تهرانی, دکتر فهیمه. (1399). درمان‌های دارویی مدرن اختلال عملکرد جنسی در زنان: مرور نقلی. , 23(9), 69-84. doi: 10.22038/ijogi.2020.17388
دکتر مرضیه ساعی قره‌ناز; مرضیه رستمی دوم; دکتر فهیمه رمضانی تهرانی. "درمان‌های دارویی مدرن اختلال عملکرد جنسی در زنان: مرور نقلی". , 23, 9, 1399, 69-84. doi: 10.22038/ijogi.2020.17388
ساعی قره‌ناز, دکتر مرضیه, رستمی دوم, مرضیه, رمضانی تهرانی, دکتر فهیمه. (1399). 'درمان‌های دارویی مدرن اختلال عملکرد جنسی در زنان: مرور نقلی', , 23(9), pp. 69-84. doi: 10.22038/ijogi.2020.17388
ساعی قره‌ناز, دکتر مرضیه, رستمی دوم, مرضیه, رمضانی تهرانی, دکتر فهیمه. درمان‌های دارویی مدرن اختلال عملکرد جنسی در زنان: مرور نقلی. , 1399; 23(9): 69-84. doi: 10.22038/ijogi.2020.17388

درمان‌های دارویی مدرن اختلال عملکرد جنسی در زنان: مرور نقلی

مجله زنان، مامایی و نازایی ایران
دوره 23، شماره 9، آذر 1399، صفحه 69-84    اصل مقاله (527.25 K)
نوع مقاله: مروری
شناسه دیجیتال (DOI): 10.22038/ijogi.2020.17388
نویسندگان
دکتر مرضیه ساعی قره‌ناز1؛ مرضیه رستمی دوم2؛ دکتر فهیمه رمضانی تهرانی* 3
1دکترای بهداشت باروری، مرکز تحقیقات اندوکرینولوژی تولیدمثل، پژوهشکده علوم غدد درون‌ریز و متابولیسم، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
2دانشجوی دکترای تخصصی پژوهشی، مرکز تحقیقات اندوکرینولوژی تولیدمثل، پژوهشکده علوم غدد درون‌ریز و متابولیسم، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
3استاد، مرکز تحقیقات اندوکرینولوژی تولیدمثل، پژوهشکده علوم غدد درون‌ریز و متابولیسم، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.
چکیده
مقدمه: اختلال عملکرد جنسی، یکی از اختلالات رایج در زنان است. تاکنون محققان درمان‌های متعددی را جهت ارتقاء سلامت جنسی زنان مورد بررسی قرار داده‌اند، مطالعه حاضر با هدف مرور درمان‌های دارویی مدرن در اختلال عملکرد جنسی زنان انجام شد.
روش‌کار: در این مطالعه مرور نقلی، جستجو در پایگاه‌های اطلاعاتی PubMed، Scopus، Web of Science، SID، Magiran و Google Scholar تا دسامبر 2019 بدون اعمال محدودیت زمانی با استفاده از کلیدواژه‌های مربوطه انجام شد. معیارهای ورود مطالعات شامل: مطالعات مشاهده‌ای، مداخله‌ای، و مروری که مطالب متناسب با اهداف این مطالعه مروری را ارائه کرده باشند. یافته‌ها، طبق دسته‌بندی موضوعی (درمان دارویی اختلال علاقه- میل جنسی، اختلال درد ناحیه تناسلی- لگنی حین دخول و اختلال ارگاسم) مورد بحث قرار گرفت.
یافته‌ها: در این مطالعه پس از بازیابی 865 مقاله، در نهایت 63 مقاله مورد بررسی نهایی قرار گرفت. بر اساس یافته‌های مطالعات،رویکردهای درمانی موجود برای درمان اختلال علاقه- میل جنسی (برملانوتید، فلیبانسرین مورد تأیید سازمان غذا و دارو آمریکا، داروهای تأیید نشده در فاز تحقیقاتی، داروهای مهارکننده فسفو دی استراز 5، تستوسترون) و رویکردهای درمانی اختلالات درد- هنگام دخول در ناحیه تناسلی- لگنی (لغزنده کننده‌ها، اسپیمفن، پراسترون، الاگولیکس مورد تأیید سازمان غذا و دارو آمریکا و تزریق بوتاکس در مرحله تحقیقاتی) می‌باشند. در رویکرد درمانی در زمینه اختلالات ارگاسمی در زنان، تاکنون، دارویی مورد تأیید قرار نگرفته است.
نتیجه‌گیری: در حال حاضر داروهای متعددی به‌صورت تأیید شده و یا تأیید نشده برای درمان اختلال عملکرد جنسی زنان مورد استفاده قرار می‌گیرند که از طریق مکانیسم‌های مختلفی نظیر افزایش جریان خون تناسلی، بهبود سطوح آندروژن‌ها و یا از طریق عملکرد بر سیستم عصبی مرکزی، اثرات بهبود ‌دهنده بر اختلال عملکرد جنسی زنان دارند. توصیه می‌شود مطالعات بیشتری در زمینه درمان اختلال عملکرد جنسی زنان در آینده انجام شود.
کلیدواژه‌ها
دارو؛ درمان؛ زنان؛ عملکرد جنسی؛ مروری
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