Coronavirus Disease 2019 in Patients with Thalassemia; Emerging Challenges | ||
| Journal of Pediatric Perspectives | ||
| مقاله 2، دوره 9، شماره 7 - شماره پیاپی 91، مهر 2021، صفحه 13895-13903 اصل مقاله (315.69 K) | ||
| نوع مقاله: review article | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2020.53675.4254 | ||
| نویسندگان | ||
| Mozhgan Hashemieh1؛ Fariba Shirvani* 2 | ||
| 1Pediatric hematologist and oncologist, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| 2Pediatric infections research center, Shaheed beheshti university of Medical Sciences, Tehran, Iran. | ||
| چکیده | ||
| Background The World Health Organization (WHO) has announced that severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) outbreak is a public health emergency requiring international concern. Thalassemia syndromes are the most prevalent monogenic hemoglobin disorder in world and Iran is located on thalassemia belt, so this type of hemoglobinopathy has a critical importance in our country. Materials and Methods: In this overview, the research was conducted by screening the relevant articles evaluating the COVID-19 in patients with thalassemia. An electronic search was performed in online data bases of Scopus, Sid.ir, EMBASE, Cochrane, Web of Science and Medline (via PubMed) with English and Persian language from December 2019 up to November 2020. Results Overall, 59 articles could be originally identified, 43 of which were excluded and 16 articles have been investigated. Thalassemic patients had a higher risk for severe clinical events due to 2019 novel corona virus. Presence of comorbidities could aggravate the course of COVID-19 in these patients. In thalassemic patients, the protocol of transfusion should not be altered. Also in asymptomatic thalassemic cases, iron chelation should not be stopped but in thalassemic patients with confirmed COVID-19 infection, iron chelation must be discontinued. Conclusion According to low number of reported cases of infected thalassemic patient with confirmed COVID-19, there are many unanswered question in management of these vulnerable patients. In this setting treatment decision need to be individualized on a case-by-case basis. In order to deliver an appropriate treatment for these patients, a teamwork between attending clinicians is of utmost importance. | ||
| کلیدواژهها | ||
| COVID-19؛ SARS-CoV-2؛ Coronavirus؛ Thalassemia؛ Hemoglobinopathy | ||
|
آمار تعداد مشاهده مقاله: 1,059 تعداد دریافت فایل اصل مقاله: 717 |
||
| تعداد نشریات | 29 |
| تعداد شمارهها | 2,328 |
| تعداد مقالات | 24,918 |
| تعداد مشاهده مقاله | 83,332,089 |
| تعداد دریافت فایل اصل مقاله | 46,261,384 |