Pourmobini, Hossein, Kazemi-arababadi, Mohammad, Salahshoor, Mohammad Reza, Roshankhah, Shiva, Taghavi, Mohammad Mohsen, Taghipour, Zahra, Shabanizadeh, Ahmad. (1400). The effect of royal jelly and silver nanoparticles on liver and kidney inflammation. , 11(3), 218-223. doi: 10.22038/ajp.2020.17045
Hossein Pourmobini; Mohammad Kazemi-arababadi; Mohammad Reza Salahshoor; Shiva Roshankhah; Mohammad Mohsen Taghavi; Zahra Taghipour; Ahmad Shabanizadeh. "The effect of royal jelly and silver nanoparticles on liver and kidney inflammation". , 11, 3, 1400, 218-223. doi: 10.22038/ajp.2020.17045
Pourmobini, Hossein, Kazemi-arababadi, Mohammad, Salahshoor, Mohammad Reza, Roshankhah, Shiva, Taghavi, Mohammad Mohsen, Taghipour, Zahra, Shabanizadeh, Ahmad. (1400). 'The effect of royal jelly and silver nanoparticles on liver and kidney inflammation', , 11(3), pp. 218-223. doi: 10.22038/ajp.2020.17045
Pourmobini, Hossein, Kazemi-arababadi, Mohammad, Salahshoor, Mohammad Reza, Roshankhah, Shiva, Taghavi, Mohammad Mohsen, Taghipour, Zahra, Shabanizadeh, Ahmad. The effect of royal jelly and silver nanoparticles on liver and kidney inflammation. , 1400; 11(3): 218-223. doi: 10.22038/ajp.2020.17045

The effect of royal jelly and silver nanoparticles on liver and kidney inflammation

Avicenna Journal of Phytomedicine
مقاله 2، دوره 11، شماره 3، مرداد و شهریور 2021، صفحه 218-223    اصل مقاله (381.91 K)
نوع مقاله: Short communication
شناسه دیجیتال (DOI): 10.22038/ajp.2020.17045
نویسندگان
Hossein Pourmobini1؛ Mohammad Kazemi-arababadi2؛ Mohammad Reza Salahshoor3؛ Shiva Roshankhah3؛ Mohammad Mohsen Taghavi4؛ Zahra Taghipour5؛ Ahmad Shabanizadeh* 6
1Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences
2Department of Immunology, Faculty of Medicine, Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3Department of Anatomical Sciences, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran
4Department of Anatomy, Faculty of Medicine, Social Determinants of Health Research center Rafsanjan University of Medical Sciences, Rafsanjan, Iran
5Department of Anatomy, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
6Department of Anatomy, Faculty of Medicine, Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
چکیده
Objective: Royal jelly (RJ) is a honey bee product for which, anti-inflammatory properties were shown in vitro. Nanoparticles, including nano-silver (NS), are plausible inflammation inducers that act by activation of immune cells and consequent production of pro-inflammatory cytokines. This project aimed to explore immunomodulatory effects of royal jelly and nano-silver on the kidney and liver.
Materials and Methods: In this project, 40 male rats were grouped as follows: 10 rats as controls, 10 rats treated with RJ; 10 rats treated with both NS and RJ and 10 rats treated with NS. Liver and kidney interleukin (IL)-1β, -2, -6, and -33 levels were determined using commercial ELISA kits.
Results: RJ reduced kidney IL-6 levels in comparison to control and NS--RJ groups. RJ and NS reduced kidney and liver IL-1β levels. Kidney IL-33 levels were decreased in the RJ and nano-silver groups in comparison to the NS--RJ group.
Conclusion: Based on this study, it may be concluded that RJ together with NS can play anti-inflammatory roles and may affect the function of immune cells.
کلیدواژه‌ها
Kidney؛ Liver؛ Nano-silver؛ Royal jelly
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