Restless legs syndrome in patients with chronic obstructive pulmonary disease | ||
| Journal of Cardio-Thoracic Medicine | ||
| مقاله 4، دوره 8، شماره 4، اسفند 2020، صفحه 707-717 اصل مقاله (245.79 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.22038/jctm.2020.47987.1272 | ||
| نویسندگان | ||
| Suchita Pant1؛ Sanjeev Kumar1؛ Rakhee Sodhi* 1؛ Rajat Ray2 | ||
| 1Pulmonologist, Department of Pulmonary Medicine, Swami Rama Himalayan University, Jollygrant, Dehradun, Uttarakhand, 248140. | ||
| 2Psychiatrist, Swami Rama Himalayan University, Jollygrant, Dehradun, Uttarakhand, 248140. | ||
| چکیده | ||
| Introduction: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death. Restless Legs Syndrome (RLS) is associated with many systemic diseases. RLS is found in many patients with COPD. There is paucity of data on this topic from India. The aim is to find the prevalence of RLS in COPD patients and its distribution in study population with respect to various demographic and clinical characteristics. Correlation between severity of RLS and COPD severity was also aimed to be evaluated. Materials and Methods: Prospective, observational study conducted in a tertiary care institute over a period of 12 months. After fulfilling the inclusion criteria the patients were categorized according to the severity of COPD using the GOLD guidelines. Diagnosis and severity of RLS was evaluated using IRLSSG criteria. Prevalence and association of RLS with COPD and its demographic and clinical characteristics was evaluated. Results: A total of 294 patients were taken which included 229 (77.9%) males and 65 females (22.1%). Mean age was 62.05 ± 10.32 years. Smoking was a more common risk factor among the patients (85.7%). 110 patients were diagnosed with RLS. A statistical significant association was found between duration of COPD and RLS (p value =0.001) and also between severity of COPD and RLS (p value=0.001). A significant positive correlation (r=0.395, p value= 0.001) between severity of COPD and RLS. Forty two (87.5%) patients with definite RLS had stage D COPD. Degree of obstruction of airways showed a statistical significant association with prevalence of RLS (p value=0.001). Conclusion: RLS showed increased prevalence in COPD patients making it crucial to screen all the COPD patients for symptoms of RLS and if required to treat the symptoms, thus improving the quality of life. | ||
| کلیدواژهها | ||
| Chronic Obstructive؛ Pulmonary Disease؛ Restless Legs Syndrome | ||
| مراجع | ||
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1. Decramer M, Londoño D, Molfino N a., Zhang P. 48. Guía de práctica clínica basada en la evidencia para la prevención, diagnóstico, tratamiento y seguimiento de la enfermedad pulmonar obstructiva crónica en población adulta. Ministerio de Salud y Protección Social-Colciencias. Minist Protección Soc Colomb. 2014;1(3):261–6.
2. Fallis A. Harrison’s Principles of Internal Medicine. In: Kasper DL, editor. McGraw Hill Education. 19th ed. New York: McGraw Hill Education; 2015. p. 2548–50.
3. Hening W, Walters AS, Allen RP, Montplaisir J, Myers A, Ferini-Strambi L. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: The REST (RLS epidemiology, symptoms, and treatment) primary care study. Sleep Med. 2004;5(3):237–46.
4. International | Restless Legs Syndrome | Study Group :: Diagnostic Criteria [Internet]. [cited 2016 Aug 30]. Available from: http://irlssg.org/diagnostic-criteria/
5. Allen RP, Earley CJ. The role of iron in restless legs syndrome. Mov Disord. 2007;440–8.
6. Patton SM, Ponnuru P, Snyder AM, Podskalny GD, Connor JR. Hypoxia-inducible factor pathway activation in restless legs syndrome patients. 2011;1329–35.
7. İn E, Turgut T, Özdemir C. Impact of Restless Legs Syndrome on the Sleep Quality in Chronic Obstructive Pulmonary Disease. Eurasian J Pulmonol. 2016;18:18–23.
8. Rangarajan S, Rangarajan S, D’Souza GA. Restless legs syndrome in an Indian urban population. Sleep Med. 2007 Dec;9(1):88–93.
9. Gupta R, Lahan V, Goel D. Translation and validation of International Restless Leg Syndrome Study Group rating scale in Hindi language. Ann Indian Acad Neurol. 2011 Oct;14(4):257–61.
10. Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study. Sleep. 2009 Jun;32(6):772–8.
11. Global Initiative for Chronic Obstructive Lung Disease Global Initiative for Chronic Obstructive Lung Disease POCKET GUIDE TO COPD DIAGNOSIS, MANAGEMENT, AND PREVENTION A Guide for Health Care Professionals. 2018.
12. Jones PW, Harding G, Berry P, Wiklund I, Chen W-H, Leidy NK. Development and first validation of the COPD Assessment Test.
13. Allen RP, Picchietti D, Hening W a, Trenkwalder C, Walters AS, Montplaisi J. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003;4(2):101–19.
14. Gupta R, Allan RP, Pundeer A, Das S, Dhyani M, Goel D. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq). Ann Indian Acad Neurol. 2015;18(3):303–8.
15. Mahesh PA, Jayaraj BS, Prahlad ST, Chaya SK, Prabhakar AK, Agarwal AN, et al. Validation of a structured questionnaire for COPD and prevalence of COPD in rural area of Mysore: A pilot study. Lung India. 2009 Jul;26(3):63–9.
16. Lavigne GL, Lobbezoo F, Rompré PH, Nielsen TA, Montplaisir J. Cigarette smoking as a risk factor or an exacerbating factor for restless legs syndrome and sleep bruxism. Sleep. 1997 Apr;20(4):290–3.
17. Lo Coco D, Mattaliano A, Coco A Lo, Randisi B. Increased frequency of restless legs syndrome in chronic obstructive pulmonary disease patients. Sleep Med. 2009;10(5):572–6.
18. Mandal T, Aydın Ş, Kanmaz D, Karasulu AL, Aras G, Tuncay E. To what extent and why are COPD and Willis-Ekbom disease associated? Sleep Breath. 2016 May 30;
19. Aras G, Kadakal F, Purisa S, Kanmaz D, Aynaci A, Isik E. Are we aware of restless legs syndrome in COPD patients who are in an exacerbation period? Frequency and probable factors related to underlying mechanism. COPD. 2011;8(6):437–43.
20. Kaplan Y, Inonu H, Yilmaz A, Ocal S. Restless legs syndrome in patients with chronic obstructive pulmonary disease. Can J Neurol Sci. 2008;35(3):352–7.
21. Benediktsdottir B, Janson C, Lindberg E, Arnardóttir ES, Olafsson I, Cook E, et al. Prevalence of restless legs syndrome among adults in Iceland and Sweden: Lung function, comorbidity, ferritin, biomarkers and quality of life. Sleep Med. 2010 Dec;11(10):1043–8.
22. Cavalcante AGM, de Bruin PFC, de Bruin VMS, Pereira EDB, Cavalcante MM, Nunes DM, et al. Restless legs syndrome, sleep impairment, and fatigue in chronic obstructive pulmonary disease. Sleep Med. 2012;13(7):842–7.
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