Association between Intracerebral Hemorrhage and Cerebral Palsy in Preterm Infant: A Systematic Review Article | ||
Journal of Pediatric Perspectives | ||
مقاله 1، دوره 8، شماره 3 - شماره پیاپی 75، خرداد 2020، صفحه 10985-10991 اصل مقاله (315.84 K) | ||
شناسه دیجیتال (DOI): 10.22038/ijp.2020.18711.3732 | ||
نویسندگان | ||
Sara Rahafard1؛ Reza Ahmadi2؛ Ayoub Tavakolian3؛ Omolbanin Heydari4؛ Hamed Jafarpour5؛ Morteza Behnamfar6؛ Roozbeh Nasibeh7؛ Farzane Ashrafinia4؛ Maryam Naseri* 8 | ||
1Pediatric Specialist, Golestan University of Medical Sciences, Gorgan, Iran. | ||
2Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran. | ||
3Emergency Medicine Department, Faculty of Medicine, Sabzevar University of Medical Science, Sabzevar, Iran. | ||
4Students Research Committee, Razi School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran. | ||
5Student Research Committee, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran. | ||
6Student Research Committee, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. | ||
7Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. | ||
8Fellowship of Pediatric Intensive Care, Department of Pediatrics, Faculty of Medicine, Mashhad university of Medical Sciences, Mashhad, Iran. | ||
چکیده | ||
Background: Intracerebral hemorrhage (ICH) is a type of intracranial bleed that occurs within the brain tissue or ventricles. The present study aimed to review the association between ICH and cerebral palsy (CP) in the preterm infants. Materials and Methods: In the systematic review, the electronic databases of Medline, Web of Science, Cochrane, EMBASE, and Scopus were systematically searched to find the relevant studies using the main keywords of (Premature OR Preterm OR Premature Infant OR Premature Birth) AND (Cerebral Palsy) AND (Brain Hemorrhage OR Intracranial Hemorrhages OR Cerebral Hemorrhage OR Putaminal Hemorrhage) up to October 26, 2019. Results: Finally, three studies with 1,730 participants were enrolled in this study. In the first study, results showed no strong association between early brain lesions with subsequent neurological consequences; in addition, the association between chorioamnionitis in intrauterine life was not substantiated with the incidence of brain lesions. In the second study, results showed progression of brain lesions and neurodevelopmental disorders like other previous studies in the follow-up of very preterm (VPT) infants up to the age of two; overall, the preterm infants are at greater risk of brain damage and neurodevelopmental disorders than term infants, independent of risk factors. In the third study, a neurological assessment was performed in the fourth, 8th, 12th, and 18th months to detect the function of the neuromotor system and CP, with higher degrees of cerebral hemorrhage associated with a higher prevalence of neurodevelopmental defects. Conclusion: Cerebral hemorrhage is considered a very important pathologic factor in preterm and low birth weight infants, which is associated with irreversible consequences of neurocognitive development. | ||
کلیدواژهها | ||
Cerebral Palsy؛ Intracerebral Hemorrhage؛ Preterm Infant | ||
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