Effects of Pectin Supplementation and 14 Weeks of Endurance Training on the Serum Atrial Natriuretic Peptide Levels and Lipid Profile of Obese Pregnant Mice | ||
| Journal of Nutrition,Fasting and Health | ||
| مقاله 12، دوره 8، شماره 1، خرداد 2020، صفحه 67-72 اصل مقاله (365.23 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22038/jnfh.2019.43983.1232 | ||
| نویسندگان | ||
| Maryam Ghasemi Hemami؛ Gholamreza Sharifi* ؛ Farzaneh Taghian؛ Mehrdad Modaresi | ||
| Department of Sports Physiology, Faculty of Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran. | ||
| چکیده | ||
| Introduction: The present study aimed to evaluate the effects of pectin supplementation and 14 weeks of endurance training on the serum atrial natriuretic peptide (ANP) levels and lipid profile of obese pregnant mice. Methods: This experimental study was conducted on 40 female laboratory mice (mean weight: 30+5 g), which were purchased from Tehran Pasteur Institute, Iran and received a high-fat diet with canola oil. The animals were randomly divided into four groups of 10, including control, pectin intake, endurance training, and pectin intake with endurance training. Training was performed for11 weeks (five sessions per week) with the intensity of 30-65% MEA on the treadmill. After becoming pregnant, the exercise groups were trained on a treadmill for three weeks five days per week with the intensity of 20-60% MEA).In the pectin groups, 400 milligrams of pectin per every kilogram of the body weight was injected gavage during days 2-19 of pregnancy. Data analysis was performed using the Kolmogorov- Smirnov test, analysis of covariance (ANCOVA), and least significant difference (LSD) test. Results: Maternal blood sampling was performed on day 19 of pregnancy to measure serum ANP, total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), LDL/high-density lipoprotein (HDL) ratio, reduced carbohydrate (RC), and HDL levels. The ANP levels decreased in the pectin group, while it increased in the exercise and exercise with pectin groups (P=0.056); however, the difference was not considered significant. Moreover, the serum levels of TC (P=0.012), TG (P=0.029), LDL (P=0.049), LDL/HDL (P=0.011), and RC (P=0.043) Significantly decreased in all the experimental groups (P=0.05), while the HDL levels significantly increased in these groups. Conclusion: According to the results, pectin consumption and exercise could effectively decrease serum TC, TG, LDL, LDL/HDL ratio, and RC and increase HDL. | ||
| کلیدواژهها | ||
| Pectin؛ endurance traning؛ Lipid profile؛ ANP | ||
| مراجع | ||
|
1.Regitz-Zagrosek V, BlomstromLundqvist C, Borghi C, et al. ESC guidelines on the management of cardiovascular diseases during pregnancy: the task force on the management of cardiovascular diseases during pregnancy of the European Society
of Cardiology (ESC). Eur Heart J 2011;32:3147–97
2.Thompson JL, Kuklina EV, Bateman BT, Callaghan WM, James AH, Grotegut CA. Medical and obstetric outcomes among pregnant women with congenital heart disease. Obstet Gynecol. 2015;126:346–354. doi: 10.1097/AOG.0000000000000973. [PMC free article] [PubMed] [CrossRef] [Google Scholar]Feb;27(1):47-72.
3.Groves T, Pandemic obesity in Europe, BMJ 2006; 333(7578): 1081.
4.Catalano PM, Shankar K. Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child. BMJ. 2017;356:j1
5.Smits-Wintjens VE, Walther FJ, Rath ME, Lindenburg IT, te Pas AB, et
al. Intravenous immunoglobulin in neonates with rhesus hemolytic disease:
arandomized controlled trial. Pediatrics. 2011 Apr;127(4):680-6. pub 2011
Mar 21
6.Saribulbul O, Alat I, Coskun S, Apaydin AZ, Yagdi T, Kiliccioglu M, et al. The role ofbrain natriuretic peptide in the prediction of cardiac performance in coronary artery bypass grafting. Tex Heart Inst J. 2003;30(4):298-304.
7.Pruszczyk P, Kostrubiec M, Bochowicz A, Styczynski G, Szulc M, Kurzyna M, et al. Nterminal
pro-brain natriuretic peptide in patients with acute pulmonary embolism. EurRespir J. 2003 Oct;22(4):649-53
8.Potter LR, Abbey-Hosch S, Dickey DM. Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions. Endocr Rev. 2006
9.Howard BW. Ruotolo G. Robbins DC.Obesity and dyslipidemia. EndocrinolMetabClin Nam. 2003. 32: 855–867
10.Tesch B.J. Herbs commonly used by women: an evidence-based review, Am J Obstet Gynecol.2013;188(5 Suppl):S44-55.
11.Sadighi J, Maftoon F, Ziaei S. Herbal medicine: Knowledge, attitude and practice in Tehran. Journal of Medicinal Plants. 2005;4(13):11-8.[Persian]
12.Munarin, F., Tanzi, M.C., and Petrini, P., 2012. Advances in biomedical applications of pectingels. International Journal of Biological Macromolecules, 51, PP: 681– 689
13.Baississe, S., Ghannem, H., Fahloul, D., and Lekbir, A., 2010. Comparison of Structure and Emulsifying Activity of Pectin Extracetd from Apple Pomace and Apricot Pulp. World Journal of Dairy & Food Sciences, 5 (1), PP: 79-84
14.Chan, S. Y. &Choo, W. S. (2013). Effect of extraction conditions on the yield and chemical properties of pectin from cocoa husks. Food Chemistry, 141(4), 3752–3758.
15Bergman, M., Djaldetti, M., Salman, H., and Bessler, H., 2010. Effect of citrus pectin on malignant cell proliferation. Biomedicine & Pharmacotherapy, 64, PP: 44–47
16.Artal R. Exercise in Pregnancy: Guidelines. September 2016 Volume 59 - Issue 3 . Clinical Obstetrics and Gynecology Saint Louis
17.Clapp JF 3rd. The effects of maternal exercise on fetal oxygenation and feto-placental growth. Eur J ObstetGynecolReprod Biol. 2003 Sep 22; 110 Suppl 1: S80-5.
18.Gharakhanlou R, Habibi A.H. The effect of submaximal swimming program on plasma ANP concentration and its relationship with essential hypertension in middle-age males. World ApplSci J 2008; 5(4): 571-575
19.Foote RS, Pearlman JD, Siegel AH, Yeo KT. Detection of exercise-induced ischemia by changes in B-type natriuretic peptides. Journal of the American College of Cardiology. 2004 Nov 16;44(10):1980-7
20.Ohba H, Takada H, Musha H, et al. Effects of prolonged strenuous exercise on plasma levels of atrial natruiuretic peptide and brain natriuetic peptide in healthy men. Am Heart J 2001; 141(5): 751-758
21.Porsti I, Kahonen M, Wu X, et al. Long-term physical exercise and atrial natriuretic peptide in obese zucker rats. PharmacolToxicol 2002; 91(1): 8- 12.
22.Vogelsang TW, Yoshiga CC, Hojgaard M, Kjaer A, Warberg J, Secher NH, et al. The plasma atrial natriuretic peptide response to arm and leg exercise in humans: effect of posture. Exp Physiol. 2006 Jul;91(4):765-71.
23.Giallauria F, Lucci R, De Lorenzo A, D’agostino M, Del Forno D, Vigorito C. Favourable effects of exercise training on N-terminal pro-brain natriuretic peptide plasma levels in elderly patients after acute myocardial infarction. Age Ageing. 2006; 35(6): 601-7
24.Shahin HS, Bigi MB, Aslani A, Daryanoosh F. Effect of professional exercises on brain natriuretic peptide. IntCardivasc Res J. 2009; 3(4): 213-6.
25.de Almeida JC, Alves CL, de Abreu LC, Sato MA, Fonseca FL, de Mello Monteiro CB, et al. Involvement of the atrial natriuretic peptide in cardiovascular pathophysiology and its relationship with exercise. International archives of medicine. 2012 Feb 7;5(1):4.
26.Bagherian, H., Ashtiani, F. Z., Fouladitajar, A. &Mohtashamy, M. (2011). Comparisons between conventional, microwave-and ultrasound-assisted methods for extraction of pectin from grapefruit. Chemical Engineering and Processing: Process Intensification, 50(11), 1237–1243.
.27.Noura S, Hafsia B, Sabah D, Sana N, Abdelfattah E, Najla H . Therapeutic effect of apple pectin in obese rats. Biomedicine & Pharmacotherapy, 2016;83: 1233-1238
28.Gnanasambandam R, Proctor A Preparation of soy hull pectin. Food Chemistry. 1999; 65: 61-7
29.Z Šefˇcíková, L Raˇcek. Effect of pectin feeding on obesity development and duodenal alkaline
30.Okura, T., Nakata, Y., and Tanaka, K. (2012). "Effects of exercise intensity on physical fitness and risk factors for coronary heart disease." Obesity research, 11(9), pp:1131-1139
31. Sun Ha Lim, Mi Young Kim, and Jongwon Lee. Apple pectin, a dietary fiber, ameliorates myocardial injury by inhibiting apoptosis in a rat model of ischemia/reperfusion Nutr Res Pract. 2014 Aug; 8(4): 391–397.
32. Songstad NT, Kaspersen KH, Hafstad AD, Basnet P,Ytrehus K, Acharya G. Effects of High IntensityInterval Training on Pregnant Rats, and the Placenta,Heart and Liver of Their Fetuses. PLoS One 2015; | ||
|
آمار تعداد مشاهده مقاله: 1,798 تعداد دریافت فایل اصل مقاله: 1,489 |
||