سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Alimohammadi, Shohreh, Jamali, Maryam, Mohsenpour, Ziba, Mohsenpour, Fatemeh, Nedadahandeh, Seyed Mahdi, Jamali, Mazyar. (1398). The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor. , 8(1), 10711-10717. doi: 10.22038/ijp.2019.44345.3673
Shohreh Alimohammadi; Maryam Jamali; Ziba Mohsenpour; Fatemeh Mohsenpour; Seyed Mahdi Nedadahandeh; Mazyar Jamali. "The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor". , 8, 1, 1398, 10711-10717. doi: 10.22038/ijp.2019.44345.3673
Alimohammadi, Shohreh, Jamali, Maryam, Mohsenpour, Ziba, Mohsenpour, Fatemeh, Nedadahandeh, Seyed Mahdi, Jamali, Mazyar. (1398). 'The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor', , 8(1), pp. 10711-10717. doi: 10.22038/ijp.2019.44345.3673
Alimohammadi, Shohreh, Jamali, Maryam, Mohsenpour, Ziba, Mohsenpour, Fatemeh, Nedadahandeh, Seyed Mahdi, Jamali, Mazyar. The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor. , 1398; 8(1): 10711-10717. doi: 10.22038/ijp.2019.44345.3673

The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor

Journal of Pediatric Perspectives
مقاله 6، دوره 8، شماره 1 - شماره پیاپی 73، فروردین 2020، صفحه 10711-10717    اصل مقاله (424.56 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2019.44345.3673
نویسندگان
Shohreh Alimohammadi1؛ Maryam Jamali2؛ Ziba Mohsenpour* 3؛ Fatemeh Mohsenpour2؛ Seyed Mahdi Nedadahandeh4؛ Mazyar Jamali5
1Perinathologist, Hamadan University of Medical Science, Hamadan, Iran.
2Obstetrician and Gynecologist, Hamedan University of Medical Science, Hamadan, Iran.
3Kowsar Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
4Anesthesiologist, Hamedan University of Medical Science, Hamadan, Iran.
5General Surgery Resident, Khorram Abad University of Medical Science, Khorram Abad, Iran.
چکیده
Background
Preterm birth with a prevalence of about 10% causes 75-95% of prenatal mortality, and one of the effective factors of it is hormonal factors. This study aimed to investigate the effect of oral medroxy progesterone on reducing preterm labor in women with a history of preterm labor.
Materials and Methods
This double-blinded clinical trial was performed on 214 pregnant women with the history of at least one preterm labor referred to midwifery clinic of Fatemieh Hospital, Shiraz, Iran, during 2017 to 2018. One hundred and seven women underwent treatment with oral medroxy progesterone (100 mg per day), and 107 individuals were prescribed placebo, and prenatal care was performed routinely. Recent pregnancy course and delivery time were compared in two groups. Data were analyzed by SPSS software version 16.0.
Results
Gestational age with a mean of 30 ± 3.89 and 36± 2.11 weeks, respectively in control and intervention groups differed significantly (P <0.05). The number of referrals to hospital due to preterm labor, the age of patients at first referral due to preterm labor, and age of delivery in both groups of receiving progesterone and placebo were significantly different (P <0.05).
Conclusion
Based on the results of the current study using 100 mg oral progesterone per day in weeks 16-36 of pregnancy was effective in reduction of preterm labor, and caused improved gestational age in mothers.
کلیدواژه‌ها
Oral Medroxy Progesterone؛ Pregnant women؛ Preterm Labor
آمار
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