سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Mohammadi, Navid, Abotorabi, Shokohossadat, Pakniat, Hamideh, Salimi, Hedieh, Chamanara, Solmaz, Hajmanoochehri, Fatemeh. (1398). Placental Calcification and Vitamin D Deficiency in Low-Risk Pregnant Women. , 8(1), 10749-10757. doi: 10.22038/ijp.2019.14030
Navid Mohammadi; Shokohossadat Abotorabi; Hamideh Pakniat; Hedieh Salimi; Solmaz Chamanara; Fatemeh Hajmanoochehri. "Placental Calcification and Vitamin D Deficiency in Low-Risk Pregnant Women". , 8, 1, 1398, 10749-10757. doi: 10.22038/ijp.2019.14030
Mohammadi, Navid, Abotorabi, Shokohossadat, Pakniat, Hamideh, Salimi, Hedieh, Chamanara, Solmaz, Hajmanoochehri, Fatemeh. (1398). 'Placental Calcification and Vitamin D Deficiency in Low-Risk Pregnant Women', , 8(1), pp. 10749-10757. doi: 10.22038/ijp.2019.14030
Mohammadi, Navid, Abotorabi, Shokohossadat, Pakniat, Hamideh, Salimi, Hedieh, Chamanara, Solmaz, Hajmanoochehri, Fatemeh. Placental Calcification and Vitamin D Deficiency in Low-Risk Pregnant Women. , 1398; 8(1): 10749-10757. doi: 10.22038/ijp.2019.14030

Placental Calcification and Vitamin D Deficiency in Low-Risk Pregnant Women

Journal of Pediatric Perspectives
مقاله 10، دوره 8، شماره 1 - شماره پیاپی 73، فروردین 2020، صفحه 10749-10757    اصل مقاله (478.3 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2019.14030
نویسندگان
Navid Mohammadi1؛ Shokohossadat Abotorabi* 2؛ Hamideh Pakniat2؛ Hedieh Salimi3؛ Solmaz Chamanara4؛ Fatemeh Hajmanoochehri5
1Department of Community and Family Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran AND Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
2Department of Obstetrics and Gynecology, School of medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
3Medical Student, School of medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
4Resident of Obstetrics and Gynecology, School of medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
5Associate Professor of Pathology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
چکیده
Background: The placental calcification is often considered as a physiologic aging process of the placenta but it may be accompanied with the altered levels of vitamin D (vit D). The aim of this study was to evaluate association between placental calcification and vit D in low risk pregnant women. 
Materials and Methods: In a case-control study eighty otherwise healthy pregnant women with a gestational age between 37-41 weeks were recruited and divided into the case (n=40), and control (n=40) groups (based on the result of the ultrasonography and according to the Grannum grading). The serum of calcium in pregnant women and vit D level in cord blood were measured by high performance liquid chromatography (HPLC). Neonatal anthropometric values were measured after birth, too.
Results: Most of the pregnant women (n=74, 92%) showed either insufficiency or deficiency of vitamin D in cord while calcium levels were normal in both groups. Serum calcium showed a significant difference between two groups [p=0.042, odds ratio (OR): 2.006, 95% confidence interval (CI): 1.024-3.928], but vitamin D did not (p=0.144, OR: 1.048, 95%CI: 0.984-1.115). Vitamin D level had a significant relationship with calcification of the placenta as well as maternal age, gestational age, and birth weight.
Conclusion: It is better to measure calcium and vitamin D in mothers with calcified placenta because the vitamin D level had a significant relationship with placental calcification and we recommend the administration of vitamin D in pregnant women.
کلیدواژه‌ها
Calcification؛ Calcium؛ Placenta؛ Pregnancy؛ Vitamin D. 
آمار
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