Ramadan Fasting and Thyroid Hormone Levels in Women with Hypothyroidism | ||
| Journal of Nutrition,Fasting and Health | ||
| مقاله 10، دوره 8، شماره 1، خرداد 2020، صفحه 55-60 اصل مقاله (307.95 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22038/jnfh.2019.42779.1217 | ||
| نویسندگان | ||
| Roghayeh Pakdel1؛ Masoud Mohebbi2؛ Nastran Rezaie3؛ Mousa-Al-Reza Hadjzadeh* 3، 4، 5 | ||
| 1Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran | ||
| 2Endocrine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 3Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 4Division of Neurocognitive Sciences, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 5Neurogenic Inflammation Research Center, Mashhad University of Medical sciences, Mashhad, Iran | ||
| چکیده | ||
| Introduction: According to some studies, Ramadan fasting causes minimal changes in the levels of thyroid hormones. The present study aimed to evaluate the impact of Ramadan fasting on the levels of thyroid hormones in fasting women with hypothyroidism and levothyroxine intake. Methods: Serum levels of free thyroxine (T4) and thyroid-stimulating hormone (TSH) were measured in 36 women with hypothyroidism aged 12-56 years, who fasted during Ramadan. Three blood samples were collected three days before Ramadan, on day 27 of Ramadan, and two months after Ramadan. In addition, the levels of hemoglobin and hematocrit (HCT) were measured during and after Ramadan. Results: The serum level of free T4 significantly decreased during Ramadan compared to before Ramadan (P<0.05). However, no significant difference was observed in the serum free T4 level before and after Ramadan. On the other hand, the TSH was higher during Ramadan compared to before Ramadan although the difference was not considered significant (normal range). TSH level reduced after Ramadan compared to during Ramadan, while no significant difference was denoted in the TSH level at the three measurement times. In addition, hemoglobin and HCT decreased significantly after Ramadan compared to during Ramadan. Conclusion: According to the results, Ramadan fasting could reduce the serum levels of free T4 in the women with hypothyroidism. However, only a slight increase was observed in the TSH levels, which was not considered significant. Further investigation is required regarding the changes caused by Ramadan fasting in the levels of hemoglobin and HCT. | ||
| کلیدواژهها | ||
| Ramadan؛ Fasting؛ Hypothyroid؛ Thyroid hormones | ||
| مراجع | ||
|
1. Lipka M, Hackett C. Why Muslims are the world’s fastest-growing religious group. Pew Research Center. 2015: 2. 2. Hajzadeh MR, Pakdel R, Hayatdavoudi P, Nematy M. Hypothyroidism and Ramadan fasting. J Fasting Health. 2014; 2(2): 80-3. 3. Bogdan A, Bouchareb B, Touitou Y. Ramadan fasting alters endocrine and neuroendocrine circadian patterns. Meal–time as a synchronizer in humans? Life Sci. 2001; 68(14): 1607-15. 4. Ziaee V, Razaei M, Ahmadinejad Z, Shaikh H, Yousefi R, Yarmohammadi L, et al. The changes of metabolic profile and weight during Ramadan fasting. Singapore Med J. 2006; 47(5): 409-14. 5. Fedail SS, Murphy D, Salih SY, Bolton CH, Harvey RF. Changes in certain blood constituents during Ramadan. Am J Clin Nutr. 1982; 36(2): 350-3. 6. Azizi F. Islamic fasting and diabetes. J Fasting Health. 2013; 1(1): 1-5. 7. Sajid KM, Akhtar M, Malik GQ. Ramadan fasting and thyroid hormone profile. J Pak Med Assoc. 1991; 41(9): 213-6. 8. Mansi K, Amneh M. Impact of Ramadan fasting on metabolism and on serum levels of some hormones among healthy Jordanian students. J Med Sci. 2007; 7(5): 755-61. 9. McDermott M. Endocrine secrets. 6th Edition. Elsevier Health Sciences; 2013. 10. Melmed S, Polonsky K, Larsen PR, Kronenberg H. Williams textbook of endocrinology. 12th Edition. Elsevier Health Sciences; 2015. 11. Martinez B, Soñanez-Organis JG, Vázquez-Medina JP, Viscarra JA, MacKenzie DS, Crocker DE, et al. Prolonged food deprivation increases mRNA expression of deiodinase 1 and 2, and thyroid hormone receptor β-1 in a fasting-adapted mammal. J Exp Biol. 2013; 216(Pt24): 4647-54. 12. Bahrayni S, Vakili R, Nematy M, Norouzy A, Hashemy SI, Ebrahimi M, et al. The effect of Ramadan fasting on thyroid hormones in 9‐13 years old pre‐menarche girls. J Fasting Health. 2013; 1(2): 46-52. 13. Sulimani RA. The effects of Ramadan fasting on thyroid functions in healthy male subjects. Nutr Res. 1988; 8(5): 549-52. 14. Ahmadinejad Z, Ziaee V, Rezaee M, Yarmohammadi L, Shaikh H, Bozorgi F, et al. The effect of Ramadan fasting on thyroid hormone profile: A cohort study. Pak J Biol Sci. 2006; 9(10): 1999-2002. 15. Hameed M, Raza SA. Management of thyroid diseases and steroid replacement in Ramadan: A review study. J Fasting Health. 2016; 4(2): 70-4. 16. Boroumand N, Hashemy SI. The effect of Ramadan fasting on endocrine system. J Fasting Health. 2015; 3(4): 148-55. 17. Karoli R, Fatima J, Chandra A, Mishra PP. Levothyroxine replacement and Ramadan fasting. Indian J Endocrinol Metab. 2013; 17(2): 318-9. 18. Trabelsi K, Rebai H, el-Abed K, Stannard SR, Khannous H, Masmoudi L, et al. Effect of Ramadan Fasting on Body Water Status Markers after a Rugby Sevens Match. Asian J Sports Med. 2011; 2(3): 186-94. 19. Zebidi A, Rached S, Dhidah M, Sadraoui M, Tabka Z, Dogui M, et al. The effect of Ramadan fasting on various blood and urinary parameters. Tunis Med. 1990; 68(5): 367-72. 20. Furuncuoglu Y, Ender K, Aras S, Yonem A. Metabolic, Biochemical and Psychiatric Alterations in Healthy Subjects During Ramadan. Pak J Nutr. 2007; 6(3): 209-11. 21. Farshidfar GHR, Yousfi H, Vakili M, Asadi Noughabi F. The effect of Ramadan fasting on hemoglobin, hematocrit and blood biochemical parameters. JRHS. 2006; 6(2): 21-7. | ||
|
آمار تعداد مشاهده مقاله: 2,187 تعداد دریافت فایل اصل مقاله: 2,085 |
||