سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Abdel Mohsen, Abdelhakeem, Amin, Mohammed, Yousef, Rasha. (1399). Acute Respiratory Tract Infection in Children under Five- Year; Study of Prevalence, Risk Factors and Outcome in Minia University Children’s Hospital, Egypt. , 8(4), 11149-11157. doi: 10.22038/ijp.2019.42502.3567
Abdelhakeem Abdel Mohsen; Mohammed Amin; Rasha Yousef. "Acute Respiratory Tract Infection in Children under Five- Year; Study of Prevalence, Risk Factors and Outcome in Minia University Children’s Hospital, Egypt". , 8, 4, 1399, 11149-11157. doi: 10.22038/ijp.2019.42502.3567
Abdel Mohsen, Abdelhakeem, Amin, Mohammed, Yousef, Rasha. (1399). 'Acute Respiratory Tract Infection in Children under Five- Year; Study of Prevalence, Risk Factors and Outcome in Minia University Children’s Hospital, Egypt', , 8(4), pp. 11149-11157. doi: 10.22038/ijp.2019.42502.3567
Abdel Mohsen, Abdelhakeem, Amin, Mohammed, Yousef, Rasha. Acute Respiratory Tract Infection in Children under Five- Year; Study of Prevalence, Risk Factors and Outcome in Minia University Children’s Hospital, Egypt. , 1399; 8(4): 11149-11157. doi: 10.22038/ijp.2019.42502.3567

Acute Respiratory Tract Infection in Children under Five- Year; Study of Prevalence, Risk Factors and Outcome in Minia University Children’s Hospital, Egypt

Journal of Pediatric Perspectives
مقاله 6، دوره 8، شماره 4 - شماره پیاپی 76، تیر 2020، صفحه 11149-11157    اصل مقاله (454.09 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2019.42502.3567
نویسندگان
Abdelhakeem Abdel Mohsen* 1؛ Mohammed Amin2؛ Rasha Yousef3
1Department of Pediatrics, El-Minia University, Egypt.
2Departments Radiology, El-Minia University, Egypt .
3Departments of Clinical Pathology, El-Minia University, Egypt.
چکیده
Background
Acute respiratory infection is still the leading cause of morbidity and mortality in children under five in many countries. We aimed to assess the incidence and risk factors predicting the outcome of Acute Respiratory Infection (ARI).
Materials and Methods
This is a hospital-based case study conducted at Minia University Children’s Hospital, Egypt from December 2016 until December 2018. Children from 2 months till five years and presented by criteria of ALRI according to WHO criteria were included in the study and evaluated for clinical presentation, risk factors and outcome. Routine investigations such as CBC, CRP and chest X-ray were done for all cases.                           
Results
Out of 586 children admitted to pulmonology unit only 215 (36.7%) fulfill the WHO criteria of ARI program, with higher incidence among infants below 6 months (48.8%) and male children (58.6%), majority of children had anemia (87%), and PEM (60%), according to WHO criteria we found that 18.6% of cases had pneumonia and 49.7% of cases had severe pneumonia. Need of change in antibiotics, duration of stay and outcomes were significantly associated in relation to pneumonia severity (p=0.04, p=0.03 and p=0.01, respectively); while need for oxygen therapy was highly significant (p=0.001) and 15% required mechanical ventilation. Lobar pneumonia (32.5%) was the most common diagnosis and sepsis was the most frequent cause of death and mortality rate was 9.3% (n=20).      
Conclusion
Young age, malnutrition and poor socioeconomic status play an important role in in the morbidity; effective management of malnutrition, improving the living standards and proper health education programs, can reduce mortality from respiratory infection in children, ARI burden and severity.
کلیدواژه‌ها
Acute Respiratory Infection؛ Children؛ Outcome؛ Risk factors
مراجع
1. Nair H, Simoes EA, Rudan I, Gessner BD, Azziz-Baumgartner E, et al. (2013) Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis. Lancet 381: 1380–90.

  1. Walker CL, Rudan I, Liu L, Nair H, Theodoratou E, et al. (2013) Global burden of childhood pneumonia and diarrhoea. Lancet 381: 1405–16.
  2. Liu L, Johnson HL, Cousens S, Perin J, Scott S, et al. (2012) Global, regional, and national causes of child mortality: An updated systematic analysis for 2010 with time trends since 2000. Lancet 379:2151–61.
  3. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, et al. (2012) Global and regional mortality from235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burdenof Disease Study 2010. Lancet 380: 2095–128.
  4. Jackson S, Mathews KH, Pulanic D, Falconer R, Rudan I, et al. (2013) Risk factors for severe acute lower respiratory infections in children: a systematic review and meta-analysis. Croat Med J 54: 110–21.
  5. Wonodi CB, Deloria-Knoll M, Feikin DR, DeLuca AN, Driscoll AJ, et al. (2012) Evaluation of risk factors for severe pneumonia in children: The pneumonia etiology research for child health study. Clinical Infectious Diseases 54 Suppl 2: S124–S131).
  6. Mertz D, Kim TH, Johnstone J, Lam PP, Science M, et al. (2013) Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis. BMJ 347: f5061. doi: 10.1136/bmj.f5061 PMID: 23974637
  7. Lozano JM (2001) Epidemiology of hypoxaemia in children with acute lower respiratory infection. Int J Tuberc Lung Dis 5: 496–504. PMID: 11409574
  8. El-Zanaty F, Ann W. Egypt Demographic and Health Survey 2008. Cairo, Egypt: Ministry of Health, El-Zanaty and Associates, and Macro International. 2009.
  9. Montasser N, Helal R and Rezq R. Assessment and classification of acute respiratory tract infections among Egyptian rural children. British Journal of Medicine and Medical Research. 2012;2(2):216-27.
11-Daniel E Roth,a Laura E Caulfield,a Majid Ezzatib & Robert E Black; Prevention and control of childhood pneumonia  Bulletin of the World Health Organization | May 2008, 86 (5)

12- WHO. Pneumonia. 2016. Available at www.who.int/mediacentre/factsheets/fs331/en/

  1. Lamberti L, Zakarija-Grkoviç I, Fischer Walker CL, Theodoratou E, Nair H, et al. (2013) reducing the risk of pneumonia morbidity and mortality in children under two: a systematic literature review and meta-analysis. BMC Public Health 13: S18.
14- Srinivasa  S, Shruthi Patel S et al. A study on distribution pattern of lower respiratory tract infections in children under 5 years in a tertiary care centre  Int J Contemp Pediatr. 2018 Mar;5(2):456-461

15- Paramesh H. Epidemiology of asthma in India. Indian J Pediatr. 2002;69(4):309-12.

  1. Udaya K, Murteli VB, Desai A. Clinical profile of children with pneumonia admitted at tertiary care hospital, Belgaum: a prospective study. Indian J Child Health. 2017;4(3):352-5.
  2. Savitha MR, Nandeeshwara SB, Kumar PMJ, Ul-Haque F, Raju CK. Modifiable risk factors for acute lower respiratory tract infections. Indian J Pediatr. 2007;74: 477-82.
  3. Broor S, Pandey RM, Ghosh M, Maitreyi RS, Lodha R, Singhal TS, et al. Risk factors for acute lower respiratory tract infections. Indian Pediatr. 2001;38:1361-7.
19- sehgal VK, Mahesh RMU, Kandat J, Ponugoti M. Clinical study of lower respiratory tract infection in children attending a tertiary care hospital. Int J Contemp Pediatr. 2017;4:1733-8.

20-Drummond  M, Pellegrin MC, Becker G, Lazzerini M, Risk factor for mortality from acute lower respiratory tract infection in children under 5 five years of age in low and middle-income countries: a systemic review and meta-analysis of observational studies. Plos One. 2015:10(1):e0116380.

21- El-Zanaty F and Associates. Egypt Demographic and Health Survey 2014. Cairo, Egypt: Ministry of Health, El-Zanaty and Associates, and Macro International. 2015

22-Khalek EMA, Abdel-Salam DM. Acute respiratory tract infections in children under 5 years of age in Upper Egypt. Int J Community Med Public Health 2016;3:1161-6.

24-Kumar AMK, Badakali AV, Mirji G, Vanaki RN, Pol R. Clinical profile and outcome of acute lower respiratory tract infection in children aged between 2 months to 5 years. Int J Contemp Pediatr. 2017;4:105-9.

25-Kabra SK, Verma IC. Acute lower respiratory tract infection. The Forgotten Pandemic. 1999;66:873-5.

26-. Ujunwa FA, Ezeonu CT. Risk factors for acute respiratory tract infections in under-five children in Enugu Southeast Nigeria. Ann Med Health Sci Res. 2014;4(1):95-99.

27-Yousif T, Khaleq B. Epidemiology of acute respiratory tract infections (ARI) among children under five years old attending Tikrit General Teaching Hospital. Middle East Journal of Family Medicine. 2006;14(3):148-52.

28-Reddaiah VP, Kapoor SK. Acute respiratory infections in under five: experience at comprehensive rural health services project hospital Ballabgarh. Indian J Community Med. 1995;20:1-4.

29-DukeT Christi MJ, Tebruegge M, la Vincent S, Raham SM,  Pneumonia in severely malnourished children in developing countries-mortality risk, aetiology and validity of WHO clinical signs: A systematic review. Trop Med Int Health. 2009;14:1173e-89

30-Mishra AS, Iyer CR, Gornale VK, Katwe N, Sushma S, Harsha PJ, et al. Clinical profile of acute lower respiratory tract infections in children between 2 months to 5 years. J Evidence Based Med Healthcare. 2015;2(35):5426-31.

آمار
تعداد مشاهده مقاله: 1,935
تعداد دریافت فایل اصل مقاله: 982