سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Ghandehari, Maryam, Dehnavi, Zahra, Razmpour, Farkhondeh, Miryan, Mahsa, Soleimani, Davood, Parizadeh, Seyed Mostafa, Jafarzadeh Esfehani, Reza, Sedaghat, Majid, Esmaily, Habibollah, Nematy, Mohsen. (1398). The Associations of Anthropometric Parameters and Hepatic Steatosis. , 8(1), 23-27. doi: 10.22038/jnfh.2019.41464.1208
Maryam Ghandehari; Zahra Dehnavi; Farkhondeh Razmpour; Mahsa Miryan; Davood Soleimani; Seyed Mostafa Parizadeh; Reza Jafarzadeh Esfehani; Majid Sedaghat; Habibollah Esmaily; Mohsen Nematy. "The Associations of Anthropometric Parameters and Hepatic Steatosis". , 8, 1, 1398, 23-27. doi: 10.22038/jnfh.2019.41464.1208
Ghandehari, Maryam, Dehnavi, Zahra, Razmpour, Farkhondeh, Miryan, Mahsa, Soleimani, Davood, Parizadeh, Seyed Mostafa, Jafarzadeh Esfehani, Reza, Sedaghat, Majid, Esmaily, Habibollah, Nematy, Mohsen. (1398). 'The Associations of Anthropometric Parameters and Hepatic Steatosis', , 8(1), pp. 23-27. doi: 10.22038/jnfh.2019.41464.1208
Ghandehari, Maryam, Dehnavi, Zahra, Razmpour, Farkhondeh, Miryan, Mahsa, Soleimani, Davood, Parizadeh, Seyed Mostafa, Jafarzadeh Esfehani, Reza, Sedaghat, Majid, Esmaily, Habibollah, Nematy, Mohsen. The Associations of Anthropometric Parameters and Hepatic Steatosis. , 1398; 8(1): 23-27. doi: 10.22038/jnfh.2019.41464.1208

The Associations of Anthropometric Parameters and Hepatic Steatosis

Journal of Nutrition,Fasting and Health
مقاله 5، دوره 8، شماره 1، خرداد 2020، صفحه 23-27    اصل مقاله (346.83 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22038/jnfh.2019.41464.1208
نویسندگان
Maryam Ghandehari1؛ Zahra Dehnavi2؛ Farkhondeh Razmpour2؛ Mahsa Miryan3؛ Davood Soleimani4؛ Seyed Mostafa Parizadeh5؛ Reza Jafarzadeh Esfehani6؛ Majid Sedaghat7؛ Habibollah Esmaily8، 9؛ Mohsen Nematy* 10، 5
1Student Research Committee, Faculty of Medicine, Islamic Azad University, Mashhad Branch, Mashhad, Iran
2Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
4Department of Nutrition, School of Nutrition sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran
5Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
6Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
7Department of Pediatric Gastroenterology, Mashhad University of Medical Sciences, Mashhad, Iran
8Department of Nutrition, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran
9Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
10Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Introduction: Non-alcoholic fatty liver disease (NAFLD) is an important health problem globally that characterized as a disease spectrum which includes simple steatosis, non-alcoholic steatohepatitis and liver fibrosis and cirrhosis. The prevalence of NAFLD has significantly increased recently. The aim of this study was to investigate the relationship between anthropometric parameters and hepatic steatosis.Methods: This cross-sectional study was performed on 415 eligible participants. Anthropometric parameters were evaluated by standard methods and fat mass was measured with bioelectrical impedance analysis. Hepatic steatosis was diagnosed using FibroScan.Results: Of the 415 participants, 308 (74.2%) had hepatic steatosis. Body mass index and waist circumference were significantly higher in patients with hepatic steatosis.  Hepatic steatosis had a significant and positive association with WC, body fat mass, and trunk fat mass. The trunk fat mass had the highest association with hepatic steatosis.  Conclusion: The present study demonstrated that anthropometric measurements are related to increase hepatic steatosis even after adjustment for age and weight. 
کلیدواژه‌ها
Non-alcoholic fatty liver disease؛ Hepatic steatosis؛ transient elastography؛ FibroScan؛ anthropometric
مراجع

1.                Parizadeh SM, Parizadeh SA, Alizade-Noghani M, Jafarzadeh-Esfehani R, Ghandehari M, Mottaghi-Moghaddam A, et al. Association between non-alcoholic fatty liver disease and colorectal cancer. Expert Rev Gastroenterol Hepatol. 2019; 13(7): 633-41.

2.                de Alwis NM, Day CP. Non-alcoholic fatty liver disease: the mist gradually clears. J Hepatol. 2008; 48 Suppl 1: S104-12

3.                Stefan N, Häring HU, Cusi K. Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies. Lancet Diabetes Endocrinol. 2019; 7(4): 313-24.

4. Younossi ZM, Blissett D, Blissett R, Henry L, Stepanova M, Younossi Y, et al. The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe. Hepatology. 2016; 64(5): 1577-86.

5.                Ahn JS, Sinn DH, Min YW, Hong SN, Kim HS, Jung SH, et al. Non‐alcoholic fatty liver diseases and risk of colorectal neoplasia. Aliment Pharmacol Ther. 2017; 45(2): 345-53.

6.                Sweet PH, Khoo T, Nguyen S. Nonalcoholic Fatty Liver Disease. Prim Care. 2017; 44(4): 599-607.

7.                Hashimoto E, Yatsuji S, Kaneda H, Yoshioka Y, Taniai M, Tokushige K, et al. The characteristics and natural history of Japanese patients with nonalcoholic fatty liver disease. Hepatol Res. 2005; 33(2): 72-6.

8.                Wong GLH. Update of liver fibrosis and steatosis with transient elastography (Fibroscan). Gastroenterol Rep (Oxf). 2013; 1(1): 19-26.

9.                Engin A. Non-Alcoholic Fatty Liver Disease. Adv Exp Med Biol. 2017; 960: 443-467.

10. Cheung O, Kapoor A, Puri P, Sistrun S, Luketic VA, Sargeant CC, et al. The impact of fat distribution on the severity of nonalcoholic fatty liver disease and metabolic syndrome. Hepatology.  2007; 46(4): 1091-100.

11. Gastaldelli A. Fatty liver disease: the hepatic manifestation of metabolic syndrome. Hypertens Res. 2010; 33(6): 546-7.

12. Rocha R, Cotrim HP, Carvalho FM, Siqueira AC, Braga H, Freitas LA. Body mass index and waist circumference in non-alcoholic fatty liver disease. J Hum Nutr Diet. 2005; 18(5): 365-70.

13. van der Poorten D, Milner KL, Hui J, Hodge A, Trenell MI, Kench JG, et al. Visceral fat: A key mediator of steatohepatitis in metabolic liver disease. Hepatology. 2008; 48(2): 449-57.

14. Weta IW, Mahadewa TG, Sutirtayasa WP, Subawa A, Sitanggang FP, Widyadharma IPE. The Comparison of Simple Anthropometric and Biochemical Parameters for Predicting Liver Steatosis in Obese Balinese Young Women. Open Access Maced J Med Sci. 2018; 6(11): 2062-6.

15.              Monteiro PA, Antunes BdMM, Silveira LS, Christofaro DGD, Fernandes RA, Freitas IF. Body composition variables as predictors of NAFLD by ultrasound in obese children and adolescents. BMC Pediatr. 2014; 14(1): 25.

16. Maher JJ. Trunk fat as a determinant of liver disease. Gastroenterology. 2010; 138(4): 1244-6.

17. Ruhl CE, Everhart JE. Trunk fat is associated with increased serum levels of alanine aminotransferase in the United States. Gastroenterology. 2010; 138(4): 1346-56.

18.              Ju DY, Choe YG, Cho YK, Shin DS, Yoo SH, Yim SH, et al. The influence of waist circumference on insulin resistance and nonalcoholic fatty liver disease in apparently healthy Korean adults. Clin Mol Hepatol. 2013; 19(2): 140-7.

19. Motamed N, Sohrabi M, Ajdarkosh H, Hemmasi G, Maadi M, Sayeedian FS, et al. Fatty liver index vs waist circumference for predicting non-alcoholic fatty liver disease. World J Gastroenterol. 2016; 22(10): 3023-30.

20. Clemente APG, Netto BDM, de Carvalho-Ferreira JP, da Silveira Campos RM, de Piano Ganen A, Tock L, et al. Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents. Rev Paul Pediatr. 2016; 34(1): 47-55.

21. Yun KE, Nam GE, Lim J, Park HS, Chang Y, Jung H-S, et al. Waist gain is associated with a higher incidence of nonalcoholic fatty liver disease in Korean adults: a cohort study. PLoS One. 2016; 11(7): e0158710.

آمار
تعداد مشاهده مقاله: 2,201
تعداد دریافت فایل اصل مقاله: 1,902