Cystic Fibrosis Patients Evaluation in the Last Decades in a Referral Center, Tehran-Iran | ||
| Journal of Pediatric Perspectives | ||
| مقاله 22، دوره 7، شماره 8 - شماره پیاپی 68، آبان 2019، صفحه 9997-10007 اصل مقاله (654.21 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2019.40329.3416 | ||
| نویسندگان | ||
| Maryam Hassanzad1؛ Masoumeh Ansari2؛ Ali Valinejadi* 3؛ Seyed Javad Sayedi4؛ Ali Akbar Velayati5 | ||
| 1Pediatric Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| 22Clinical Research Development Unit, Kowsar Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran. | ||
| 3Social Determinants of Health Research Center, Department of Health Information Technology, Semnan University of Medical Sciences, Semnan, Iran. | ||
| 4Assistant Prof of Pediatric Pulmonology, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 5Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| چکیده | ||
| Background Cystic fibrosis (CF) is the most prevalent lethal chronic genetic and multivariate disease, widespread in Iranian population. The aim of this study was to evaluate the condition of patients with CF from various dimensions in the last decades in Iran. Materials and Methods In this cross-sectional study the data were collected from disease registrydatabase of CF patients in Pediatric Respiratory Disease Research Center in Masih Daneshvari, Tehran, Iran. The patients were divided into female and male.The data were collected based on province, birthplace province, marital status, and degree of education, parental consanguinity ratio, age, and age of onset of symptoms, age of onset of diagnosis and body mass index (BMI). Results Majority of patients (n=169, 59.3%) were male, born in Tehran province (n=81, 28.4%), and live in Tehran province (n=102, 35.8%). Majority of parents (61.1%, n=174) had consanguineous relation and the rest (n=94, 33%) did not have any consanguineous relation. Results show that mean of age, age of diagnosis, mean for expression of first symptoms and mean of time interval between the onset of symptoms and the diagnosis of the disease were 14.52, 2.51, 6.57, and 4.07 years, respectively. Results showed that high percentage of patients (n=191, 67%) had lower BMI (<18.50), and low percentage (n=3, 1.1%) showed higher BMI (>25). Correlation coefficient also showed positive relation between start age of symptoms and diagnosis age of disease. Conclusion In Iran, CF is a multisystem disease and age for its expression is different. Since mean for time interval between the onset of symptoms and the diagnosis of the disease | ||
| کلیدواژهها | ||
| Children؛ Cystic fibrosis؛ Growth pattern؛ Iran؛ Symptoms | ||
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