Assessment and Comparison of Homogeneity and Conformity Indexes in Step-and-Shoot, Compensator-Based Intensity Modulated Radiation Therapy (IMRT) and Three-Dimensional Conformal Radiation Therapy (3D CRT) in Prostate Cancer | ||
| Iranian Journal of Medical Physics | ||
| مقاله 393، دوره 15، Special Issue-12th. Iranian Congress of Medical Physics، بهمن و اسفند 2018، صفحه 406-406 | ||
| نوع مقاله: Conference Proceedings | ||
| شناسه دیجیتال (DOI): 10.22038/ijmp.2018.13068 | ||
| نویسندگان | ||
| Kaveh Shirani Tak Abi1؛ Hassan Ali Nedaie2؛ Hussain Gharaati3؛ Hossein Hassani4؛ Marzieh Salimi5؛ Reza KhodaBakhshi6؛ Farid Nezhad Dadgar7؛ Malihe Rezaie Yazdi8؛ Maryam Rezaie Yazdi9 | ||
| 1Kaveh Shirani Tak Abi, Medical Physicist of Sina Radiotherapy Oncology Department, Bu Ali Hospital, Tehran, Iran. | ||
| 2Hassan Ali Nedaie, Assistant Prof. of Medical Physics, Radiotherapy Oncology Department, Tehran University of Medical Sciences, Tehran, Iran. | ||
| 3Hussain Gharaati, Prof. of Medical Physics, Radiotherapy Oncology Department, Tehran University of Medical Sciences, Tehran, Iran. | ||
| 4Hossein Hassani, M. Sc of Medical Radiation Engineering, Department of Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran. | ||
| 5Marzieh Salimi, PhD. Candidate of Medical Physics, Medical Physics and Engineering Department, Tehran University of Medical Sciences, Tehran, Iran. | ||
| 6Reza KhodaBakhshi, Radiation Oncologist, Consultant and Executive Director of Sina Radiotherapy Oncology Department, Bu Ali Hospital, Tehran, Iran. | ||
| 7Farid Nezhad Dadgar, Assistance Prof. of Radiation Oncology, Sina Radiotherapy Oncology Department, Bu Ali Hospital, Islamic Azad University, Medical College, Tehran, Iran. | ||
| 8Malihe Rezaie Yazdi, Medical physicist of Iran Mehr Radiotherapy Oncology Department, Iran Mehr Hospital, Birjand, Iran. | ||
| 9Maryam Rezaie Yazdi, Medical physicist of Iran Mehr Radiotherapy Oncology Department, Iran Mehr Hospital, Birjand, Iran. | ||
| چکیده | ||
| Introduction: Intensity modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3D CRT) are two treatment modalities in prostate cancer, which provide acceptable dose distribution in tumor region with sparing the surrounding normal tissues. IMRT is based on inverse planning optimization; in which, intensity of beams is modified by using multileaf collimators and also compensators with optimum shapes in step and shoot (SAS) and compensator-based method, respectively. Materials and Methods: Prescribed dose was 80 Gy for both IMRT procedures and 70 Gy for 3D CRT. Treatment plans of 15 prostate cancer candidates were compared to target the minimum dose, maximum dose, V 76 Gy (for IMRT plans) V 66.5 Gy (for 3D CRT), mean dose, conformity index (CI), and homogeneity index (HI). Results: Dose conformity in compensators-based IMRT was better than SAS and 3D CRT. The same outcome was also achieved for homogeneity index. The target coverage was achieved 95% of prescribed dose to 95% of planning target volume (PTV) in 3D CRT and 95% of prescribed dose to 98% of PTV in IMRT methods. IMRT increases maximum dose of tumor region, improves CI and HI of target volume, and also reduces dose of organs at risks. Conclusion: Results of this study showed that both IMRT methods provide better target coverage in comparison of 3D CRT. In SAS technique, maximum dose reduced compared with compensator-based IMRT while, in the later method, CI and HI improved; it must be mentioned that 3D CRT also had the acceptable HI and CI results. IMRT approaches represented better homogeneity and conformity over 3D CRT and in comparison of two IMRT methods, all acceptable results can be achieved in compensator IMRT. | ||
| کلیدواژهها | ||
| IMRT؛ 3DCRT؛ conformity index؛ homogeneity index؛ step and shoot؛ compensator | ||
|
آمار تعداد مشاهده مقاله: 896 |
||
| تعداد نشریات | 29 |
| تعداد شمارهها | 2,324 |
| تعداد مقالات | 24,864 |
| تعداد مشاهده مقاله | 82,812,701 |
| تعداد دریافت فایل اصل مقاله | 45,865,543 |