سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Salehipoor, Hassan, Afzali, Behzad, Akrami, Rahim, Ghorat, Fereshteh, Niktabe, Zahra, Sahebkar, Mohammad. (1397). Effect of Topical Chamomile Oil (Matricaria chamomile L.) as a Supplementary Method on Colic Symptoms in Infants: A Randomized Placebo-controlled Clinical Trial. , 10(1), 15-22. doi: 10.22038/ijn.2019.32270.1448
Hassan Salehipoor; Behzad Afzali; Rahim Akrami; Fereshteh Ghorat; Zahra Niktabe; Mohammad Sahebkar. "Effect of Topical Chamomile Oil (Matricaria chamomile L.) as a Supplementary Method on Colic Symptoms in Infants: A Randomized Placebo-controlled Clinical Trial". , 10, 1, 1397, 15-22. doi: 10.22038/ijn.2019.32270.1448
Salehipoor, Hassan, Afzali, Behzad, Akrami, Rahim, Ghorat, Fereshteh, Niktabe, Zahra, Sahebkar, Mohammad. (1397). 'Effect of Topical Chamomile Oil (Matricaria chamomile L.) as a Supplementary Method on Colic Symptoms in Infants: A Randomized Placebo-controlled Clinical Trial', , 10(1), pp. 15-22. doi: 10.22038/ijn.2019.32270.1448
Salehipoor, Hassan, Afzali, Behzad, Akrami, Rahim, Ghorat, Fereshteh, Niktabe, Zahra, Sahebkar, Mohammad. Effect of Topical Chamomile Oil (Matricaria chamomile L.) as a Supplementary Method on Colic Symptoms in Infants: A Randomized Placebo-controlled Clinical Trial. , 1397; 10(1): 15-22. doi: 10.22038/ijn.2019.32270.1448

Effect of Topical Chamomile Oil (Matricaria chamomile L.) as a Supplementary Method on Colic Symptoms in Infants: A Randomized Placebo-controlled Clinical Trial

Iranian Journal of Neonatology
مقاله 3، دوره 10، شماره 1، خرداد 2019، صفحه 15-22    اصل مقاله (414.85 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22038/ijn.2019.32270.1448
نویسندگان
Hassan Salehipoor1؛ Behzad Afzali2؛ Rahim Akrami3؛ Fereshteh Ghorat* 4؛ Zahra Niktabe5؛ Mohammad Sahebkar2
1Vasei Hospital, Clinical Research Development Center, Sabzevar University of Medical Sciences, Sabzevar, Iran
2Student Research Committee, Sabzevar University of Medical Sciences, Sabzevar, Iran
3Department of Epidemiology and Biostatistics, School of Public Health, Sabzevar University of Medical Sciences, Sabzevar, Iran
4Traditional and Complementary Medicine Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran
5Department of Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran
چکیده
Background: The aim of this study was to evaluate the efficacy of the topical use of chamomile oil as a complementary method in the improvement of infantile colic symptoms.
Methods: This randomized controlled trial was carried out on 74 infants with colic at Sabzevar University of Medical Sciences in Sabzevar, Iran. The infants were randomly allocated into two groups. In the intervention group, chamomile oil was applied topically on the abdominal region three times a day for 14 days. The placebo group received paraffin oil in a similar manner. A data collection form was daily filled out for all infants by their parents. Number and duration of crying episodes and duration of sleep were assessed at the baseline and on the 7th and 14th days of the intervention.
Results: Results showed that there was a significant difference in the crying time of the two groups on days 7 and 14 as compared to that at the baseline (P=0.03 and P=0.002, respectively). There was a significant increase in sleep duration only on the 14th day of treatment as compared with that at the baseline (P=0.01). Although the number of crying episodes in both groups decreased, there was no significant difference between the two groups (P=0.08). Based on the regression test, although the values obtained on days 1 and 7 were not statistically significant, compared to those at the baseline, the number of crying episodes decreased on the 14th day (95% CI: -115.39 to -15.04; P=0.012).
Conclusion: Topical consumption of chamomile oil may be used as a complementary, safe, and cost-effective way to improve and reduce the symptoms of infantile colic.
کلیدواژه‌ها
Infant؛ Chamomile؛ Colic؛ Complementary medicine
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