Effects of Fasting on Glucagon-like peptide-1 hormone (GLP-1), and Lipid Profile Indices in Obese and Thin Women | ||
| Journal of Pediatric Perspectives | ||
| مقاله 6، دوره 7، شماره 3 - شماره پیاپی 63، خرداد 2019، صفحه 9095-9102 اصل مقاله (365.76 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2018.36085.3147 | ||
| نویسندگان | ||
| Shahrbanoo Haghighi1؛ Seyed Reza Attarzade Hosseini2؛ Masoud Saleh Moghaddam1؛ Majid Rajabian3؛ Mohammad Ali Kiani4؛ Habibolah Taghizade Moghaddam5؛ Seyed Majid Sezavar Kamali6 | ||
| 1Department of Biochemistry, Payame Noor University, Mashhad, Iran. | ||
| 2Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Ferdowsi University of Mashhad, Mashhad, Iran. | ||
| 3Department of Biochemistry, Payame Noor University, Tehran, Iran. | ||
| 4Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 5Department of Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 6PhD in Laboratory Science, Mashhad, Iran. | ||
| چکیده | ||
| Introduction: Glucagon-like peptide-1 hormone (GLP-1) contributes to the regulation of insulin and glucose concentration. However, the effects of fasting on GLP-1 response in different people has not been determined yet. The aim of the present research was to investigate the effect of fasting on GLP-1 and the lipid profile of obese and thin women. Materials and methods: In this research, 25 obese and thin women whose age ranged from 35 to 45 years were selected through a convenient sampling method and were divided into two groups of obese (n=12, body mass index ˃30 kg/m2) and thin (n=13, body mass index=18-20 kg/m2). GLP-1 in both groups was measured in four phases: 3 days before the beginning of Ramadan, 14 days after the beginning of Ramadan, 28 days after the beginning of Ramadan and 2 weeks after the end of Ramadan. Repeated –measure ANOVA was used to statistically analyse the data. Results: GLP-1 was reduced from phase 1 to 3 of the research. However, it was increased after Ramadan. In the thin group, GLP-1 was increased in 14 days of fasting, but did not show any change at the end of Ramadan, and also two weeks after this month. However, none of these changes were statistically significant. The two groups did not diverge from each other significantly in any of the phases. Conclusion: The present findings showed that fasting has no significant effect on the GLP-1 and lipid profile indices of the obese and thin women. | ||
| کلیدواژهها | ||
| fasting؛ Glucagon-like peptide-1 hormone؛ Obese؛ Women | ||
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