Eosinophilic Mucin Rhinosinusitis in Iranian Patients Undergoing Endoscopic Sinus Surgery | ||
| Iranian Journal of Otorhinolaryngology | ||
| مقاله 6، دوره 30، شماره 6 - شماره پیاپی 101، بهمن و اسفند 2018، صفحه 347-353 اصل مقاله (321.26 K) | ||
| نوع مقاله: Original | ||
| شناسه دیجیتال (DOI): 10.22038/ijorl.2018.30430.1996 | ||
| نویسندگان | ||
| Jahangir Ghorbani1؛ Ali Hosseini Vajari2؛ Guitti Pourdowlat3؛ Parisa Ghasemi* 2؛ Yousef Eskandari2؛ Keyvan Ghasemi4 | ||
| 1Chronic Respiratory Diseases Research Center,National Research Institute of Tubeclosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| 2Department of Otolaryngology,DR. Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| 3Chronic Respiratory Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. | ||
| 4Medical student ,Student Research Committee,Arak University of Medical Sciences, Arak ,Iran. | ||
| چکیده | ||
| Introduction: Eosinophilic mucin rhinosinusitis is a type of chronic rhinosinusitis (CRS). Diagnosis and treatment of this condition play a significant role in reducing the patients’ clinical symptoms. This type of rhinosinusitis has a higher relapse rate, compared to the other types. This disease is more resistant to treatment and more dependent on corticosteroid therapy, compared to the other types of rhinosinusitis. Regarding this, the present study was designed to evaluate the frequency of eosinophilic mucin rhinosinusitis in patients undergoing sinus surgery in a tertiary referral center and examine some clinical and laboratory characteristics regarding this type of rhinosinusitis. Materials and Methods: This cross-sectional observational study was performed on patients over the age of 16 years, who were diagnosed with CRS in the otolaryngology clinic of a referral tertiary-level hospital, and were candidates for endoscopic sinus surgery. Based on the detection of eosinophilic mucin, the subjects were divided into two groups of eosinophilic mucin and non-eosinophilic mucin rhinosinusitis (controls). The groups were compared in terms of sino-nasal outcome test (SNOT-22) scores, Lund-Mackay staging scores, osteitis status, immunoglobulin E (IgE) level, and eosinophilia. Results: In this study, 46 subjects participated, 29 (63%) cases of whom had eosinophilic mucin. The SNOT-22 score and serum IgE level were significantly higher in the eosinophilic mucin group, compared to those in the control group. Osteitis and Lund-Mackay scores were also higher in the eosinophilic mucin group than those in the control group; however, this difference was not statistically significant. Conclusion: Patients with eosinophilic mucin rhinosinusitis showed a more severe clinical involvement. Seemingly, the Iranian patients have a lower and higher frequency of eosinophilic mucin rhinosinusitis, compared to the patients from the Western countries and East Asia, respectively. | ||
| کلیدواژهها | ||
| Chronic؛ Eosinophilic؛ Rhinitis؛ IgE؛ Sinusitis؛ Mucin؛ Nasal Polyps؛ Osteitis | ||
| مراجع | ||
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1. Bhattacharyya N. Contemporary assessment of the disease burden of sinusitis. American journal of rhinology & allergy, 2009; 23(4): 392-5. 2. Tomassen P, Vandeplas G, Van Zele T, Cardell LO, Arebro J, Olze H, et al. Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers. J Allergy Clin Immunol, 2016; 137: 1449-56. 3. Akdis CA, Bachert C, Cingi C, Dykewicz MS, Hellings PW, Naclerio RM, et al. Endotypes and phenotypes of chronic rhinosinusitis: A PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol, 2013; 131: 1479- 90. 4. Ryan MW. Diseases associated with chronic rhinosinusitis: what is the significance? Current opinion in otolaryngology & head and neck surgery. 2008; 16(3): 231-6. 5. Poznanovic SA, Kingdom TT. Total Ige levels and peripheral Eosinophilia correlation with mucosal diseases based on computed tomographic imaging of the paranasal sinus. Arch Otolaryngol Head Neck Surg. 2007; 133(7): 701-4. 6. Ponikau JU, Sherris DA, Kephart GM, Kern EB, Congdon DJ, Adolphson CR. Striking deposition of toxic eosinophil major basic protein in mucus: Implications for chronic rhinosinusitis. J Allergy Clin Immunol, 2005; 116: 362-9.
7. Ramadan HH, Quraishi HA. Allergic mucin sinusitis without fungus. American journal of rhinology. 1997; 11(2): 145-7.
8. Piao YS, Jin YL, Li X, Zhou Q, Wang AL, Liu HG. Clinicopathologic evaluation of 36 cases of allergic fungal sinusitis.Zhonghua Bing Li XueZaZhi. 2009; 38(2): 95-9.
9. Pant H, Kette FE, Smith WB, Macardle PJ, Wormald PJ. Eosinophilic Mucus Chronic Rhinosinusitis: Clinical Subgroups or a Homogeneous Pathogenic Entity? Laryngoscope. 2006; 116: 1241–7.
10. Lara JF, Gomez JD. Allergic mucin with and without fungus: a comparative clinicopathologic analysis. Archives of pathology & laboratory medicine, 2001; 125(11): 1442-7. 11. Kern EB, Sherris D, Stergiou AM, Katz LM, Rosenblatt LC, Ponikau J. Diagnosis and treatment of chronic rhinosinusitis: focus on intranasal Amphotericin B.TherClin Risk Manag. 2007; 3(2): 319-25.
12. Lee SH, Kim HJ, Lee JW, Yoon YH, Kim YM, Rha KS. Categorization and Clinicopathological Features of Chronic Rhinosinusitis With Eosinophilic Mucin in a Korean Population. Clinical and Experimental Otorhinolaryn-gology.2015; 18(1): 39-45.
13. N Uri, O Ronen, T Marshak, O Parpara, M Nashashibi, M Gruber.Allergic fungal sinusitis and eosinophilic mucin Rhinosinusitis: diagnostic criteria. The Journal of Laryngology & Otology. 2013; 127: 867–71.
14. Meltzer EO, Hamilos DL, Hadley JA, Lanza DC, Marple BF, Nicklas RA, et al. Rhinosinusitis: Establishing definitions for clinical research and patient care. Otolaryngology–Head and Neck Surgery. 2004; 131(6): 1-62.
et al. The Reliability and Validity of the Persian Version of Sinonasal Outcome Test 22 (Snot22) Questionnaires. Iran Red Crescent Med J.2013; 15(5): 404-8.
16. Georgalas C, Videler W, Freling N.Global osteitis scoring scaleand chronic rhinosinusitis: a marker of revision surgery. Clin. Otolaryngol. 2010; 35:455-61
17. Braun H, Buzina W, Freudenschuss K, Beham A, Stammberger H. Eosinophilic Fungal Rhinosinusitis: A Common Disorder in Europe? Laryngoscope.2003;113: 264-9.
18. Ferguson BJ. Eosinophilic mucin rhinosinusitis: a distinct clinicopathological entity. The Laryngoscope. 2000; 110(5):799-813. 19. Ponikau JU, Sherris DA, Kern EB, Homburger HA, Frigas E, Gaffey TA, et al. The Diagnosis and Incidence of Allergic Fungal Sinusitis. Mayo Clin Proc.1999; 74:877-84.
20. Cao PP, Li HB, Wang BF, Wang SB, You XJ, Cui YH, et al. Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese. American Academy of Allergy, Asthma & Immunology.2009. 124: 478-83. 21. Zhang N, Holtappels G, Claeys C, Huang G, van Cauwenberge P, Bachert C. Pattern of inflammation and impact of Staphylococcus aureus enterotoxins in nasal polyps from southern China. American Journal of Rhinology. 2016; 13:34:56.
22. Aeumjaturapat S, ISIPRADIT P, Saengpanich S, KeelawatS. Eosinophilic Mucin Rhinosinusitis nicopathological Presentation. J Med Assoc Thai. 2003; 86: 420-4. 23. Ikeda K, Shiozawa A, Ono N, Kusunoki T, Hirotsu M, Homma H, et al. Subclassification of Chronic Rhinosinusitis With Nasal Polyp Based on Eosinophil and Neutrophil. Laryngoscope.2013;123: 1–9.
24. Sakuma Y, Ishitoya J, Komatsu M, Shiono O, Hirama M, Yamashita Y, et al. New clinical diagnostic criteria for eosinophilic chronic rhinosinusitis.Auris Nasus Larynx .2011;38 :583–8.
25. Kato A. Immunopathologyof chronic rhinosinusitis. Allergology International, 2015; 64(2):121-130. | ||
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