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Akbarian Rad, Zahra, Esmaeilzadeh, Seddigheh, Haghshenas Mojaveri, Mohsen, Bagherzadeh, Mojgan, Javanian, Mostafa. (1397). Maternal Recto-Vaginal Organisms and Surface Skin Colonization in Infants. , 9(3), 14-19. doi: 10.22038/ijn.2018.28024.1375
Zahra Akbarian Rad; Seddigheh Esmaeilzadeh; Mohsen Haghshenas Mojaveri; Mojgan Bagherzadeh; Mostafa Javanian. "Maternal Recto-Vaginal Organisms and Surface Skin Colonization in Infants". , 9, 3, 1397, 14-19. doi: 10.22038/ijn.2018.28024.1375
Akbarian Rad, Zahra, Esmaeilzadeh, Seddigheh, Haghshenas Mojaveri, Mohsen, Bagherzadeh, Mojgan, Javanian, Mostafa. (1397). 'Maternal Recto-Vaginal Organisms and Surface Skin Colonization in Infants', , 9(3), pp. 14-19. doi: 10.22038/ijn.2018.28024.1375
Akbarian Rad, Zahra, Esmaeilzadeh, Seddigheh, Haghshenas Mojaveri, Mohsen, Bagherzadeh, Mojgan, Javanian, Mostafa. Maternal Recto-Vaginal Organisms and Surface Skin Colonization in Infants. , 1397; 9(3): 14-19. doi: 10.22038/ijn.2018.28024.1375

Maternal Recto-Vaginal Organisms and Surface Skin Colonization in Infants

Iranian Journal of Neonatology
مقاله 3، دوره 9، شماره 3، آذر 2018، صفحه 14-19    اصل مقاله (770.59 K)
شناسه دیجیتال (DOI): 10.22038/ijn.2018.28024.1375
نویسندگان
Zahra Akbarian Rad1؛ Seddigheh Esmaeilzadeh2؛ Mohsen Haghshenas Mojaveri3؛ Mojgan Bagherzadeh4؛ Mostafa Javanian* 5
1Non-Communicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran
2Infertility and Health Reproductive Research Center, Babol University of Medical Sciences, Babol, Iran
3Clinical Research Development Unit of Rohani Hospital, Babol University of Medical Sciences, Babol, Iran
4Babol University of Medical Sciences, Babol, Iran
56Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran 7 Department of Statistic and Epidemiology, Babol University of Medical Sciences, Babol, Iran.
چکیده
Background: Early-onset sepsis is a common cause of neonatal mortality and mainly occurs due to the colonized microorganisms in the maternal recto-vaginal area. The present study aimed to evaluate the effects of maternal risk factors on recto-vaginal colonization and transmission rate of micro-flora from mothers to infants.
Methods: Upon admission, two samples were obtained from the distal third of vagina and rectum of mothers using sterile cotton swabs. Six hours after birth, sterile swab samples were collected from the external ear canal, nose, groin, and umbilicus of the infants. The samples were transferred to the laboratory on Stuart transport medium. Afterwards, the samples were transferred to standard culture media within 24 hours. Transmission rate of organisms was calculated based on the maternal and neonatal findings.
Results: In total, 13 bacterial and fungal species were detected in the samples. Escherichia coli was the most frequent gram-negative organism in the rectal and vaginal cultures (29.34%) with the transmission rate of 49.4% to the infants. Infants of the mothers with premature rupture of membranes (PROM) had significant Enterobacter cloacaecolonization. In addition, frequency of Candida albicans was higher in the mothers with gestational hypertension (21.4%) compared to non-hypertensive women (4.9%). Infants requiring advanced cardiopulmonary resuscitation (CPR) had significantly higher E. coli colonization (45.1%) compared to those not needing CPR (27.6%).
Conclusion: According to the results, gram-negative bacteria (E. coli and Enterobacteriaceae ) were the most frequent organisms in the maternal recto-vaginal area and body surface of the neonates in our clinical setting. Therefore, chemoprophylaxis is recommended for these organisms in prolonged PROM.
 
کلیدواژه‌ها
Communication disorders؛ Congenital hypothyroidism؛ Diagnosis؛ Mass screening؛ Sensorineural hearing loss
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