Differentiation of Cocaine-Induced Midline Destructive Lesions from ANCA-Associated Vasculitis | ||
| Iranian Journal of Otorhinolaryngology | ||
| مقاله 10، دوره 30، شماره 5 - شماره پیاپی 100، آذر و دی 2018، صفحه 309-313 اصل مقاله (508.96 K) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.22038/ijorl.2018.25210.1817 | ||
| نویسندگان | ||
| Alireza Mirzaei1؛ Mozhdeh Zabihiyeganeh* 1؛ Ala Haqiqi2 | ||
| 1Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran. | ||
| 2Department of General Medicine, St. George’s University Hospitals NHS Foundation Trust, London, UK. | ||
| چکیده | ||
| Introduction: Cocaine-induced midline destructive lesions (CIMDL) are complications of regular nasal cocaine inhalation. CIMDL can mimic systemic diseases with positive anti-neutrophil cytoplasmic antibodies (ANCA), such as granulomatosis with polyangiitis (GPA). Case Report: In this article, we describe the case of a young woman who presented with nasal perforation induced by cocaine, along with positive perinuclear ANCA test (proteinase 3 antigen), misdiagnosed as limited GPA. The patient was treated with immunosuppressive therapy, which partially improved her symptoms. Admittance of cocaine use aided in the diagnosis of CIMDL. This patient was advised to stop cocaine use. Three-month follow-up revealed no further complications. Conclusion: Considering the seropositivity of ANCA in both CIMDL and GPA, early diagnosis of CIMDL and its differentiation from GPA is crucial, and clinicians play an important role in this regard. Lack of distinct histologic characteristics of vasculitis or unresponsiveness to standard therapeutic regimens may favor the diagnosis of CIMDL syndrome. It is crucial to recognize that these conditions may have similar presentations, so that undesired and potentially toxic treatments can be prevented. | ||
| کلیدواژهها | ||
| Anti-neutrophil cytoplasmic antibody؛ Cocaine؛ Granulomatosis | ||
| مراجع | ||
|
1. Rachapalli S, Kiely P .Cocaine‐induced midline destructive lesions mimicking ENT‐limited Wegener's granulomatosis. Scand J Rheumatol. 2008; 37:477–80.
2. Bakhshaee M, Khadivi E, Naseri Sadr M, Esmatinia F. Nasal septum perforation due to methamphetamine abuse. Iran J Otorhinolaryngol. 2013; 25:53–6.
3. Stahelin L, de Magalhães Souza Fialho SC, Neves FS, Junckes L, Werner de Castro GR, et al. Cocaine-induced midline destruction lesions with positive ANCA test, mimicking Wegener’s granulomatosis. Rev Bras Reumatol. 2012;52:431–7.
4. Trimarchi M, Bertazzoni G Bussi M. Cocaine induced midline destructive lesions. Rhinology. 2014;52:104–11.
5. Alamino-Perez RS, Espinoza LR. Vasculitis mimics: Cocaine-induced midline destructive lesions. Am J Med Sci. 2013;346:430–1.
6.Armengot M, Garcia-Lliberos A, Gomez MJ, Navarro A, Martorell A. Sinonasal involvement in systemic vasculitides and cocaine-induced midline destructive lesions: Diagnostic controversies. Allergy Rhinol. 2013;4:e94–e9.
7. Berman M, Paran D, Elkayam O. Cocaine-induced vasculitis. Rambam Maimonides Med J. 2016; 7 (4).
8. Gregorini G, Facchetti F, Morassi L, Manfredini C, Nicolai P, Trimarchi M, et al. Positive ANCA tests in patients with cocaine induced midline destructive lesions (CIMDL). Clin Experiment Immunol (Suppl). 2000;120: 59.
9. Wiesner O, Russell KA, Lee AS, Jenne DE, Trimarchi M, Gregorini G, et al. Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine‐induced midline destructive lesions but not autoimmune vasculitis. Arthritis Rheumatism. 2004; 50:2954–65.
10. Goodger NM, Wang J Pogrel MA. Palatal and nasal necrosis resulting from cocaine misuse. Br Dent J. 2005;198:333–4.
11. Gottschlich S, Ambrosch P, Kramkowski D, Laudien M, Buchelt T, Gross WL, et al. Head and neck manifestations of Wegener’s granulomatosis. Rhinol. 2006;44:227–233.
12. Roca B. Epistaxis and systemic disease. Acta Otorrinolaringol Esp. 2009;60:456–458.
13. Fuchs HA, Tanner SB. Granulomatous disorders of the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg. 2009;17:23–27.
14. Peikert T, Finkielman JD, Hummel AM, McKenney ME, Gregorini G, Trimarchi M, et al. Functional characterization of antineutrophil cytoplasmic antibodies in patients with cocaine-induced midline destructive lesions. Arthritis Rheum. 2008;58:1546–51.
15. Stegeman CA, Tervaert JWC, Sluiter WJ, Manson WL, de Jong PE, Kallenberg CG. Association of chronic nasal carriage of Staphylococcus aureus and higher relapse rates in Wegener granulomatosis.Ann Int Med.1994;120: 12–17.
16. Simsek S, de Vries XH, Jol JA, Spoelstra-de Man AM, Nanayakkara PW, Smulders YM, et al. Sino-nasal bony and cartilaginous destruction associated with cocaine abuse, S. aureus and antineutrophil cytoplasmic antibodies. Neth J Med. 2006;64:248–251.
17. Graf J, Lynch K, Yeh CL, Tarter L, Richman N, Nguyen T, et al. Purpura, cutaneous necrosis, and antineutrophil cytoplasmic antibodies associated with levamisole-adulterated cocaine. Arthritis Rheum. 2011;63:3998–4001.
18. Abdul-Karim R, Ryan C, Rangel C, Emmett M. Levamisole-induced vasculitis. Proc (Bayl Univ Med Cent). 2013;26(2):163.
19. Van der Poel NA, Schot LJ, Menger DJ. Local complications of intranasal cocaine abuse: diagnostic and therapeutic guidelines. Ned Tijdschr Geneeskd. 2013;157:A6035. | ||
|
آمار تعداد مشاهده مقاله: 651 تعداد دریافت فایل اصل مقاله: 454 |
||