Comparison of Elevated Liver Enzymes in Type 2 Diabetic Patients in User and Non-User of Statin | ||
| Journal of Pediatric Perspectives | ||
| مقاله 15، دوره 6، شماره 12 - شماره پیاپی 60، اسفند 2018، صفحه 8757-8764 اصل مقاله (345.96 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2018.34136.3015 | ||
| نویسندگان | ||
| Majid Rajabian* 1؛ Elham Hussein Nejad2؛ Habibolah Taghizade Moghaddam3 | ||
| 1Faculty Member of Payame Noor University, Tehran, Iran. | ||
| 2Master of Biochemistry, Payame Noor University, Mashhad, Iran. | ||
| 3Department of Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| چکیده | ||
| Background: Type-2 diabetes is a risk factor for progressive non-alcoholic fatty liver disease and the majority of diabetic patients have blood lipid disorders, so they take statin drugs. Statins have the adverse effects such as liver dysfunction and increase in liver enzymes. The purpose of this study was to compare the liver enzymes in type 2 diabetic patients who are user and non-user of statin. Methods: In a case-control study, increased liver enzymes (ALT and AST > 40 U/L) were measured in blood samples of 200 type II diabetic patients (with and without statin consumption) who referred to Mashhad Diabetes Clinic in Mashhad city (Iran), during May to November 2017. Levels of liver enzymes and anthropometric indices were measured for both groups. Liver enzymes were assessed at the baseline of two groups. The SPSS 20th software was used for data analysis. Results: The mean of Body mass index in two groups of diabetic patients with and without statin consumption had a significant difference (p | ||
| کلیدواژهها | ||
| ALT؛ AST؛ Diabetes Mellitus؛ Statins | ||
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