Frequency and Clinical Manifestations of Pediatric Brucellosis in Iran: A Systematic Review | ||
| Journal of Pediatric Perspectives | ||
| مقاله 13، دوره 7، شماره 2 - شماره پیاپی 62، اردیبهشت 2019، صفحه 9037-9047 اصل مقاله (688.11 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2018.33178.2927 | ||
| نویسندگان | ||
| Shirin Djalalinia1؛ Reza Arjmand* 2؛ Mehri Gholami3؛ Yasaman Shaker4؛ Sahar Saeedi Moghaddam5؛ Kumars Pourrostami6؛ Omid Safari6؛ Nasrin Elahimehr7؛ Saeed Nik Khah7؛ Ehsan Zahmatkesh7؛ Esfandiar Najafi Tavana7؛ Mostafa Qorbani* 2 | ||
| 1Deputy of Research and Technology, Ministry of Health and Medical Education, Tehran, Iran AND Non–communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. | ||
| 2Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran. | ||
| 3Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran. 5Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran. | ||
| 4Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran. | ||
| 5Non–communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. | ||
| 6Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran. | ||
| 7Department of Pediatric, Emam Ali Hospital, Alborz University of Medical Sciences, Karaj, Iran. | ||
| چکیده | ||
| Background Brucellosis is a zoonotic disease that is widely distributed throughout the developing countries. Children are considered as at risk groups for infection. The aim of this study was to assess the frequency and clinical manifestations of Brucellosis in Iranian children and adolescents. Materials and Methods: We systematically searched international databases; ISI, Medline (via PubMed), Scopus, and national databases Irandoc, Barakat knowledge network system, Magiran, and Scientific Information Database (SID). The search strategy was developed based on main terms of "Brucellosis," "Brucella fever", "Gibraltar", "Rock Fever", "Undulant Fever", "Cyprus Fever", "Malta Fever", and "Bang Disease". Results: A total of 885 studies were identified, from them a total of 12 studies that were conducted between 2001 and 2016 were included. Following the relevancy assessments and quality control, data from the 1,429 participants were presented in our review. The age of the patients ranged from 2 to 18 years. Only one out of twelve studies provided the prevalence of 4.30% and 3.4 incidence. Studies varied greatly in reporting high risk behavior of animal contact (8.4 to76.0%) and unpasteurized dairy (22.4 to 91.6%). Conclusion Our finding reveals the disparity of reported prevalence and clinical manifestations of Brucellosis in Iranian children. Fever and joint pain were the most frequent reported signs. Differences in study design, measurement tools and methods, and sub population sampling, does not provide the possibility of aggregation of data for more comprehensive inference. | ||
| کلیدواژهها | ||
| Brucellosis؛ Children؛ Clinical manifestations؛ Iran | ||
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