Artificial intelligence investigation of three silicates bioceramics-magnetite bio-nanocomposite: Hyperthermia and biomedical applications | ||
| Nanomedicine Journal | ||
| مقاله 6، دوره 5، شماره 3، مهر 2018، صفحه 163-171 اصل مقاله (1.34 M) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22038/nmj.2018.005.0006 | ||
| نویسندگان | ||
| Amir Hussein Montazeran؛ Saeed Saber Samandari؛ Amirsalar Khandan* | ||
| New Technologies Research Center, Amirkabir University of Technology, Tehran, Iran | ||
| چکیده | ||
| Objective(s): Bioactive silicate ceramics have favorable features for applying as off-the-shelf bone and artificial tissue. Calcium silicate can enhance the generation of an immediate bond with host bone without an intervening rough surface in the bone layer. However, the silicate bioceramics have some drawback regarding their mechanical properties and chemical stabilities. Materials and Methods: In this study, magnetite nanoparticles (MNPs) as reinforcement were added to the three silicate bioceramics to investigate the physical and mechanical properties as well as their magnetic behavior as a case study and compare with other calcium silicate nanocomposite which are excellent candidates for hyperthermia applications. Then the artificial neural network (ANN) applied to the previous data to predict the mechanical and biological behavior of the bio-nanocomposite as output parameters. A predicted model was enhanced using ANN to measure the optimum size and reinforcement amount of the magnetite bio-nanocomposite. The results of the fabricated bio-nanocomposite were extracted experimentally corresponding to different MNPs weight fractions compared to the predicted model. Results: The X-ray diffraction (XRD), scan electron microscopy (SEM) technique were used to compare the porosity and porous tissue microstructure. Thereafter, an analytical solution is presented to express explicitly the physical and mechanical responses of the bulk/scaffold bio-nanocomposite. Conclusion: The obtained results showed the potential application of these calculations and analyses in a wide range of numerical studies. The comparison presented within the test and predicted values showed that the modeling outcomes were close to testing values. | ||
| کلیدواژهها | ||
| Magnetite nanoparticle؛ Nanocomposite؛ Artificial neural network؛ Biomedicine؛ Tissue engineering | ||
| مراجع | ||
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1.Poinern GE, Brundavanam S, Fawcett D. Biomedical magnesium alloys: a review of material properties, surface modifications and potential as a biodegradable orthopaedic implant. Am J Biomed Eng. 2012; 2(6): 218-240. 2.Karamian E, Abdellahi M, Khandan A, Abdellah S. Introducing the fluorine doped natural hydroxyapatite-titania nanobiocomposite ceramic. J Alloys Compd. 2016: 15; 679: 375-383. 3.Khandan A, Abdellahi M, Ozada N, Ghayour H. Study of the bioactivity, wettability and hardness behaviour of the bovine hydroxyapatite-diopside bio-nanocomposite coating. J Taiwan Inst Chem Eng. 2016: 1; 60: 538-546. 4.Sharafabadi AK, Abdellahi M, Kazemi A, Khandan A, Ozada N. A novel and economical route for synthesizing akermanite (Ca2MgSi2O7) nano-bioceramic. Mater. Sci. Eng., C. 2017: 1; 71: 1072-1078. 5.Najafinezhad A, Abdellahi M, Ghayour H, Soheily A, Chami A, Khandan A. A comparative study on the synthesis mechanism, bioactivity and mechanical properties of three silicate bioceramics. Mater. Sci. Eng., C. 2017:1; 72: 259-267. 6.Kazemi A, Abdellahi M, Khajeh-Sharafabadi A, Khandan A, Ozada N. Study of in vitro bioactivity and mechanical properties of diopside nano-bioceramic synthesized by a facile method using eggshell as raw material. Mater. Sci. Eng., C. 2017: 1; 71: 604-610. 7.Iannotti V, Adamiano A, Ausanio G, Lanotte L, Aquilanti G, Coey JM, Lantieri M, Spina G, Fittipaldi M, Margaris G, Trohidou K. Fe-Doping-Induced Magnetism in Nano-Hydroxyapatites. Inorg. Chem. 2017: 5; 56(8): 4446-4458. 8.Hajinasab A, Saber-Samandari S, Ahmadi S, Alamara K. Preparation and characterization of a biocompatible magnetic scaffold for biomedical engineering. Mater Chem Phys. 2018: 15; 204: 378-387. 9.Saber-Samandari S, Saber-Samandari S, Joneidi-Yekta H, Mohseni M. Adsorption of anionic and cationic dyes from aqueous solution using gelatin-based magnetic nanocomposite beads comprising carboxylic acid functionalized carbon nanotube. Chem Eng J. 2017: 15; 308: 1133-1144. 10.Saber-Samandari S, Yekta H, Saber-Samandari S. Effect of Iron Substitution in Hydroxyapatite Matrix on Swelling Properties of Composite Bead. JOM. 2015: 9; 1: 19-25. 11.Khandan A, Ozada N, Saber-Samandari S, Nejad MG. On the mechanical and biological properties of bredigite-magnetite (Ca7MgSi4O16-Fe3O4) nanocomposite scaffolds. Ceram Int. 2018: 15; 44(3): 3141-3148. 12.Abdellahi M, Karamian E, Najafinezhad A, Ranjabar F, Chami A, Khandan A. Diopside-magnetite; A novel nanocomposite for hyperthermia applications. J Mech Behav Biomed Mater. 2018:1; 77: 534-538. 13.Farzin A, Fathi M, Emadi R. Multifunctional magnetic nanostructured hardystonite scaffold for hyperthermia, drug delivery and tissue engineering applications. Mater. Sci. Eng., C. 2017: 1; 70: 21-31. 14.Najafinezhad A, Abdellahi M, Saber-Samandari S, Ghayour H, Khandan A. Hydroxyapatite-M-type strontium hexaferrite: A new composite for hyperthermia applications. J Alloys Compd. 2018: 15; 734: 290-300. 15.Ghayour H, Abdellahi M, Ozada N, Jabbrzare S, Khandan A. Hyperthermia application of zinc doped nickel ferrite nanoparticles. J Phys Chem Solids. 2017: 1; 111: 464-472. 16.Ghayour H, Abdellahi M, Nejad MG, Khandan A, Saber-Samandari S. Study of the effect of the Zn2+ content on the anisotropy and specific absorption rate of the cobalt ferrite: the application of Co1− xZnxFe2O4 ferrite for magnetic hyperthermia. J AUST CERAM SOC. 2017: 1-8. 17.Abdellahi M, Najfinezhad A, Saber-Samanadari S, Khandan A, Ghayour H. Zn and Zr co-doped M-type strontium hexaferrite: Synthesis, characterization and hyperthermia application. Chin. J. Phys. 2017:2028. 18.Khandan A, Ozada N. Bredigite-Magnetite (Ca7MgSi4O16-Fe3O4) nanoparticles: A study on their magnetic properties. J Alloys Compd. 2017: 5; 726: 729-736. 19.Ghayour H, Abdellahi M, Bahmanpour M, Khandan A. Simulation of dielectric behavior in RFeO $ $ _ {3} $ $3 orthoferrite ceramics (R= rare earth metals). J Comput Electron. 2016: 1; 15(4): 1275-1283. 20.Arinzeh TL, Tran T, Mcalary J, Daculsi G. A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation. Biomaterials. 2005: 1; 26(17): 3631-3638. 21.Saber-Samandari S, Saber-Samandari S, Ghonjizade-Samani F, Aghazadeh J, Sadeghi A. Bioactivity evaluation of novel nanocomposite scaffolds for bone tissue engineering: The impact of hydroxyapatite. Ceram Int. 2016: 1; 42(9): 11055-11062. 22.Abdellahi M, Bahmanpour H, Bahmanpour M. The best conditions for minimizing the synthesis time of nanocomposites during high energy ball milling: modeling and optimizing. Ceram. Int. 2014: 1; 40(7): 9675-9692. 23.Abdellahi M. A new predictive model for calculating the hardness of metal matrix nanocomposites produced by mechanical alloying. J. Mater. Res. 2013; 28(23): 3270-3278. 24.Abdellahi M, Bahmanpour M. A novel technology for minimizing the synthesis time of nanostructured powders in planetary mills. Mater. Res. 2014; 17(3): 781-791. 25.Abdellahi M, Ghayour H, Bahmanpour M. Effect of process parameters and synthesis method on the performance of thermoelectric ceramics: a novel simulation. Ceram. Int. 2015: 1; 41(5): 6991-6998. 26.Abdellahi M, Najafinezhad A, Ghayour H, Saber-Samandari S, Khandan A. Preparing diopside nanoparticle scaffolds via space holder method: Simulation of the compressive strength and porosity. J Mech Behav Biomed Mater. 2017; 1; 72: 171-181. 27.Kokubo T, Takadama H. How useful is SBF in predicting in vivo bone bioactivity?. Biomaterials. 2006: 1; 27(15): 2907-2915. 28.Ferreira C. Gene expression programming in problem solving. InSoft computing and industry 2002. 635-653. 29.Aghadavoudi F, Golestanian H, Tadi Beni Y. Investigating the effects of resin crosslinking ratio on mechanical properties of epoxy‐based nanocomposites using molecular dynamics. Polym. Compos. 2017:1; 38(S1). 30.Aghadavoudi, F., Golestanian, H., & Tadi Beni, Y. Investigation of CNT Defects on Mechanical Behavior of Cross linked Epoxy based Nanocomposites by Molecular Dynamics. 31.Aghadavoudi, F., Golestanian, H., & Tadi Beni, Y. Investigating the effects of CNT aspect ratio and agglomeration on elastic constants of crosslinked polymer nanocomposite using multiscale modeling. Polym. Compos. 32.Sahmani S, Khandan A, Saber-Samandari S, Aghdam MM. Nonlinear bending and instability analysis of bioceramics composed with magnetite nanoparticles: Fabrication, characterization, and simulation. Ceram. Int. 2018. 33.Razavi M, Khandan A. Safety, regulatory issues, long-term biotoxicity, and the processing environment. InNanobiomaterials Science, Development and Evaluation. 2017; 261-279. 34.Khandan A, Jazayeri H, Fahmy MD, Razavi M. Hydrogels: Types, Structure, Properties, and Applications. J. Biomater. Tissue Eng. 2017; 3; 4: 143-169. 35.Sen T, Sebastianelli A, Bruce IJ. Mesoporous silica− magnetite nanocomposite: fabrication and applications in magnetic bioseparations. JACS. 2006: 7; 128(22): 7130-7131. 36.Sahmani S, Khandan A, Saber-Samandari S, Aghdam MM. Vibrations of beam-type implants made of 3D printed bredigite-magnetite bio-nanocomposite scaffolds under axial compression: Application, communication and simulation. Ceram. Int. 2018. 37.Khandan A, Karamian E, Mehdikhani-Nahrkhalaji M, Mirmohammadi H, Farzadi A, Ozada N, Heidarshenas B, Zamani K. Influence of spark plasma sintering and baghdadite powder on mechanical properties of hydroxyapatite. Procedia Mater Sci. 2015 Jan 1; 11:183-189. 38.Khandan, A., Ozada, N., & Karamian, E. (2015). Novel microstructure mechanical activated nano composites for tissue engineering applications. J Bioeng Biomed Sci, 5(1), 1. 39.Salami MA, Kaveian F, Rafienia M, Saber-Samandari S, Khandan A, Naeimi M. Electrospun polycaprolactone/lignin-based nanocomposite as a novel tissue scaffold for biomedical applications. J Med Signals Sens. 2017; 7(4): 228. 40.Xu Y, Geng Z, Gao Z, Zhuo X, Li B, Cui Z, Zhu S, Liang Y, Li Z, Yang X. Effects of both Sr and Mg substitution on compositions of biphasic calcium phosphate derived from hydrothermal method. Int J Appl Ceram. Technol. 2018; 1. 41.Khandan A, Karamian E, Bonakdarchian M. Mechanochemical synthesis evaluation of nanocrystalline bone-derived bioceramic powder using for bone tissue engineering. Dent Hypoth. 2014: 1; 5(4): 155. 42.Karamian E, Nasehi A, Saber-Samandari S, Khandan A. Fabrication of hydroxyapatite-baghdadite nanocomposite scaffolds coated by PCL/Bioglass with polyurethane polymeric sponge technique. Nanomed J. 2017; 4(3): 177-183. 43.Heydary HA, Karamian E, Poorazizi E, Heydaripour J, Khandan A. Electrospun of polymer/bioceramic nanocomposite as a new soft tissue for biomedical applications. J Asian Ceram Soc. 2015:1; 3(4): 417-425. 44.Saber-Samandari S, Yekta H, Ahmadi S, Alamara K. The role of titanium dioxide on the morphology, microstructure, and bioactivity of grafted cellulose/hydroxyapatite nanocomposites for a potential application in bone repair. Int. J. Biol. Macromol. 2018; 106: 481-488. | ||
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