Raji-amirhasani, Alireza, Joukar, Siavash, Naderi boldaji, Vida, Bejeshk, Mohammad-Abbas. (1397). Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats. , 21(6), 558-563. doi: 10.22038/ijbms.2018.24796.6165
Alireza Raji-amirhasani; Siavash Joukar; Vida Naderi boldaji; Mohammad-Abbas Bejeshk. "Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats". , 21, 6, 1397, 558-563. doi: 10.22038/ijbms.2018.24796.6165
Raji-amirhasani, Alireza, Joukar, Siavash, Naderi boldaji, Vida, Bejeshk, Mohammad-Abbas. (1397). 'Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats', , 21(6), pp. 558-563. doi: 10.22038/ijbms.2018.24796.6165
Raji-amirhasani, Alireza, Joukar, Siavash, Naderi boldaji, Vida, Bejeshk, Mohammad-Abbas. Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats. , 1397; 21(6): 558-563. doi: 10.22038/ijbms.2018.24796.6165

Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats

Iranian Journal of Basic Medical Sciences
مقاله 2، دوره 21، شماره 6، شهریور 2018، صفحه 558-563    اصل مقاله (550.76 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22038/ijbms.2018.24796.6165
نویسندگان
Alireza Raji-amirhasani1، 2؛ Siavash Joukar* 3، 1؛ Vida Naderi boldaji4، 1؛ Mohammad-Abbas Bejeshk4، 1
1Department of Physiology and Pharmacology, Kerman University of Medical Sciences, Kerman, Iran
2Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
3Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Science, Kerman, Iran
4Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
چکیده
Objective(s): Considering the lack of information, the effects of mild endurance exercise plus blood flow restriction (BFR) on electrocardiographic parameters, hypertrophy index, and expression of angiotensin II receptors type 1 (AT1R) and type 2 (AT2R) and apelin receptor (APJ) were assessed in hearts of old male rats.
Materials and Methods: Animal were grouped as control (CTL), Sham (Sh), lower extremities blood flow restriction (BFR), exercise (Ex), Sham + exercise (Sh + Ex), and blood flow restriction + exercise (BFR + Ex).
Results: Exercise plus BFR significantly decreased the corrected QT (QTc) interval (PConclusion: Mild endurance exercise plus BFR can alter the expression of angiotensin II and apelin receptors that leads to cardiac hypertrophy and improves the ventricular conductivity of aging rats.
کلیدواژه‌ها
Aging؛ Angiotensin II receptors؛ Apelin receptor؛ Blood flow restriction؛ Endurance Exercise
مراجع
آمار
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