Mirsadraee, Majid, Tavakoli, Afsaneh, Ghorani, Vahideh, Ghafari, Shadi. (1397). Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments. , 8(5), 399-407. doi: 10.22038/ajp.2018.25278.1925
Majid Mirsadraee; Afsaneh Tavakoli; Vahideh Ghorani; Shadi Ghafari. "Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments". , 8, 5, 1397, 399-407. doi: 10.22038/ajp.2018.25278.1925
Mirsadraee, Majid, Tavakoli, Afsaneh, Ghorani, Vahideh, Ghafari, Shadi. (1397). 'Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments', , 8(5), pp. 399-407. doi: 10.22038/ajp.2018.25278.1925
Mirsadraee, Majid, Tavakoli, Afsaneh, Ghorani, Vahideh, Ghafari, Shadi. Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments. , 1397; 8(5): 399-407. doi: 10.22038/ajp.2018.25278.1925

Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments

Avicenna Journal of Phytomedicine
مقاله 236، دوره 8، شماره 5، آذر و دی 2018، صفحه 399-407    اصل مقاله (545.4 K)
نوع مقاله: Original Research Article
شناسه دیجیتال (DOI): 10.22038/ajp.2018.25278.1925
نویسندگان
Majid Mirsadraee* 1؛ Afsaneh Tavakoli2؛ Vahideh Ghorani3؛ Shadi Ghafari4
1Department of Internal medicine, Faculty of Medicine, Islamic Azad University-Mashhad Branch, Mashhad, Iran
2Innovative Medical Research Center, Department of pharmacology, Mashhad Branch, Islamic Azad University, Mashhad, Iran
3Neurogenic Inflammation Research Centre and Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Biologist, Shahid Hasehemi Nezhad Research center, Kavosh high school, Ministry of Education, Mashhad, Iran
چکیده
Objective: The present study aimed to determine the effects of Rosmarinus officinalis (R. officinalis) and Platanus orientalis(P. orientalis) extracts on asthma.
Materials and Methods: We conducted a randomized, double-blind, active-comparator study to evaluate the effect of P. orientalis and R. officinalis extracts on asthmatic patients resistant to routine treatment.The subjects were randomly divided into three groups receiving P. orientalis and R. officinalis extracts alone or in combination. The primary endpoints were clinical findings, spirometry, exhaled nitric oxide (FENO) and Asthma Control Test (ACT) assessed over the one-month treatment period.
Results: ACT score showed significant improvement after treatment with R. officinalis (p<0.05) but not with P. orientalis. Clinical evaluations showed that cough, sputum production and wheezing were significantly improved in R. officinalis group (p Conclusion: R. officinalis extract showed promising results in treatment of resistant asthma. Further studies to find the most effective components of these herbal medicines are recommended.
کلیدواژه‌ها
Asthma؛ R. officinalis؛ P. orientalis؛ Sycamore؛ Rosmarinic acid
مراجع
آمار
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