Current Concepts in Scaffolding for Bone Tissue Engineering | ||
| The Archives of Bone and Joint Surgery | ||
| مقاله 2، دوره 6، شماره 2، خرداد 2018، صفحه 90-99 اصل مقاله (571.33 K) | ||
| نوع مقاله: CURRENT CONCEPTS REVIEW | ||
| شناسه دیجیتال (DOI): 10.22038/abjs.2018.26340.1713 | ||
| نویسندگان | ||
| Toktam Ghassemi1؛ Azadeh Shahroodi2؛ Mohammad H. Ebrahimzadeh3؛ Alireza Mousavian3؛ Jebraeel Movaffagh2؛ Ali Moradi PhD* 3 | ||
| 1Department of Chemical Engineering, Ferdowsi University of Mashhad, Mashhad, Iran | ||
| 2Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 3Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| چکیده | ||
| Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bone tissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials and functional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissue engineering. While osteoconductive materials such as hydroxyapatite and tricalcium phosphate ceramics as well as some biodegradable polymers are suggested, much interest has recently focused on the use of osteoinductive materials like demineralized bone matrix or bone derivatives. However, physiochemical modifications in terms of porosity, mechanical strength, cell adhesion, biocompatibility, cell proliferation, mineralization and osteogenic differentiation are required. This paper reviews studies on bone tissue engineering from the biomaterial point of view in scaffolding. | ||
| کلیدواژهها | ||
| Bone tissue engineering؛ Regeneration؛ Scaffolds | ||
| مراجع | ||
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